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The revised Third Edition of The Prokaryotes, acclaimed as a classic reference in the field, offers new and updated articles by experts from around the world on taxa of relevance to medicine, ecology and industry. Entries combine phylogenetic and systematic data with insights into genetics, physiology and application. Existing entries have been revised to incorporate rapid progress and technological innovation. The new edition improves on the lucid presentation, logical layout and abundance of illustrations that readers rely on, adding color illustration throughout. Expanded to seven volumes in its print form, the new edition adds a new, searchable online version.
This unique reference/text presents the basic theory and practical applications of metabolic engineering (ME). It offers systematic analysis of complex metabolic pathways and ways of employing recombinant DNA techniques to alter cell behavior, metabolic patterns, and product formation. Treating ME as a distinct subfield of genetic engineering, the book demonstrates new means of enabling cells to produce valuable proteins, polypeptides, and primary and secondary metabolites. Written by more than 35 leading international experts in the field, this book discusses metabolic engineering in plant and mammalian cells, bacteria, and yeasts and assesses metabolic engineering applications in agriculture, pharmaceuticals, and environmental systems. It illuminates the potential of the "cell factory" model for production of chemicals and therapeutics and examines methods for developing new antiviral and antibacterial molecules and effective gene and somatic-cell therapies. Metabolic Engineering also addresses the use of metabolic flux analysis, metabolic control analysis, and online metabolic flux analysis.
For many of us, these simple rewards are suf The purpose of this briefforeword is unchanged from the first edition; it is simply to make you, ficiently gratifying so that we have chosen to the reader, hungry for the scientific feast that spend our scientific lives studying these unusual follows. These four volumes on the prokaryotes creatures. In these endeavors many of the strat offer an expanded scientific menu that displays egies and tools as well as much of the philos the biochemical depth and remarkable physi ophy may be traced to the Delft School, passed ological and morphological diversity of prokar on to us by our teachers, Martinus Beijerinck, yote life. The size ofthe volumes might...
First multi-year cumulation covers six years: 1965-70.