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This concise book is addressed to researchers, clinical investigators, as well as practicing physicians and surgeons who are interested in the fields of clinical research and trials. It covers some important topics related to clinical trials including an introduction to clinical trials, some aspects concerning clinical trials in pediatric age group, and the unique aspects of the design of clinical trials on stem cell therapy.
The basic researches and clinical studies on gallbladder diseases continue to advance at a rapid pace. The chapters in this book were written by recognized medical experts and researchers from North America, Europe, Asia, and Africa and aim to provide the state-of-the-art reviews on the current knowledge and advances in research and management of gallbladder diseases. This book includes the most recent advances in that field, particularly, the immunogenetic basis of cholecystitis, noncoding RNAs in gallbladder cancer, the diagnostic pitfalls and timing of management of acute cholecystitis, the incidental gallbladder cancer, the surgical management of gallbladder cancer, laparoscopic cholecystectomy in special conditions, and robot-assisted cholecystectomy.
Longmire, called it a "hostile" organ because it welcomes malignant cells and sepsis so warmly, bleeds so copiously, and is often the ?rst organ to be injured in blunt abdominal trauma. To balance these negative factors, the liver has two great attributes: its ability to regenerate after massive loss of substance, and its ability, in many cases, to forgive insult. This book covers a wide spectrum of topics including, history of liver surgery, surgical anatomy of the liver, techniques of liver resection, benign and malignant liver tumors, portal hypertension, and liver trauma. Some important topics were covered in more than one chapter like liver trauma, portal hypertension and pediatric liver tumors.
This book is addressed to researchers, practicing physicians, and surgeons in the field of organ transplantation, as well as the medical students, residents, and fellows. The topics covered include the religious concepts in organ transplantation, embryonic organ transplantation, tolerance, normothermic graft perfusion, pharmacogenetics of immunosuppressors, viral transmission in organ transplantation, pediatric and split-liver transplantation, portopulmonary hypertension, mechanical circulatory support, ex vivo lung perfusion, and ABO-incompatible kidney transplantation.
This book presents the most recent advances in the field of liver diseases and surgery, including the remarkable advances in Hepatitis C therapy, liver tumors, injuries, cysts, resections, transplantation, and preoperative management of patients with liver diseases. The editors are the dean and vice deans of the National Liver Institute, Menoufia University, a dedicated international center of excellence and a leading medical institution in the Middle East for the diagnosis and management of liver diseases and advanced training and research in hepatobiliary sciences. The authors are leading experts from four continents across the globe (North America, Europe, Asia, and Africa). In other words, the book team reflects an international dream team of experts in the area of liver diseases.
This book covers a wide spectrum of topics including, but not limited to, the technical issues in living and deceased donor liver transplant procedures, cell and experimental liver transplantation, and the complications of liver transplantation. Some of the very important topics, such as the arterial reconstruction in living donor liver transplantation, biliary complications, and the post-transplant-lymphoprolifrative disorders (PTLD), have been covered in more than one chapter.
Liver cancers result in considerable amount of financial and social burden. On the other hand, researches and clinical studies related to liver cancers continue to advance at a rapid pace. The chapters in this book provide state-of-the-art reviews on the current knowledge and advances in research and management of liver cancers. It includes the most recent advances in that field, particularly, hepatocarcinogenesis and the potential role of intestinal microbiota, nonalcoholic steatohepatitis, cancer stem cells, aldehyde dehydrogenase-1, and hepatitis B virus. This book also discusses the methods of diagnosis of HCC, the minimally invasive therapies for liver cancers, living donor liver transplantation for HCC, surgical management of liver metastases from colorectal cancers, and assessment and optimization for the future liver remnant.
The basic researches and clinical studies on biliary tree diseases continue to advance at a rapid pace. The articles in this book were written by recognized medical experts and researchers from North America, Europe, Asia, and Africa and aim to provide state-of-the-art reviews on the current knowledge and advances in the surgery of the biliary tree. It includes the most recent advances in that field, particularly cholangiocarcinoma, biliary tree injuries, and biliary cysts.
Soft-tissue reconstruction for a variety of surgical conditions, such as abdominal wall hernia, hiatal hernia, stomal hernia, anal fistula and pelvic floor replacement remains a challenge. There is an insufficient level of high-quality evidence in the literature on the value of bioprosthetics for soft-tissue reconstruction. An expanded knowledge about their clinical efficacy is urgently needed.
This volume reviews cutting-edge innovations in blockchain technology that are propelling the healthcare industry into a new era of efficiency and security. It brings 14 reviews contributed by experts in blockchain and Web3 technologies into a single volume. Each contribution includes a summary for easy understanding and scientific references for advanced readers. Key Themes: Empowering Decentralized Healthcare: Learn about the future of decentralized healthcare, powered by blockchain, ensuring a seamless and patient-centric experience. Clinical Trials: Discover how blockchain is reshaping clinical trials, offering a glimpse into a future of optimized medical research. Data Security: Uncover...