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Considerable progress in our understanding of tumor promotion has been made by cancer researchers throughout the world. In addition, scientists in several other disciplines have made significant contributions in elucidating the pleiotropic effects of tumor promotion. This international symposium was specifically convened to review research progress in these areas and to consider the relevance of these findings to human cancer causation and prevention. The proceedings include the contributions of leading researchers from Europe, Japan and the USA. Several papers report the exciting progress made in understanding how tumor promoters act at the cellular and biochemical levels. Elsewhere attention is focused on tumor promotion as an important phase in the occurrence of certain human tumors. It is hoped that advances in the understanding of the mechanism of tumor promotion in experimental systems will lead to new and effective approaches to human cancer prevention. The proceedings will be of interest and value to researchers working in cancer research, biochemistry, molecular genetics, mutagenesis and cell biology.
This book discusses toxic Microcystis and the toxins from various viewpoints such as classification, cultivation, occurrences in lakes, and relations to zooplankton. The text presents new information on the chemistry, analytical chemistry, toxicology, molecular modeling, and liver tumor promotion of the toxins. Microcystis species are described in relation to morphological features, allozyme genotype, and toxin content. Seasonal changes of Microcystis population are described with special references to toxic species and composition of the toxins. Chemical characteristics of microcystins are reviewed and the process for identification of microcystins is described.
Advances in Cancer Research
Marine organisms produce a wide array of toxins, many of which are not only structurally unusual, but also show potent and interesting modes of action. Since the discovery of tetrodotoxin, a pufferfish toxin, as a potent and selective blocker of Na+ channels in 1964, it has been widely used as a research tool in pharmacological and physiological research. This has led to the identification of a number of important biological functions for Na+ channels. In recent years, much biological research has been carried out at molecular and cellular levels, and therefore selective inhibitors of enzymes and selective antagonist/agonists of receptors and channels have become increasingly important research tools. Accordingly, interest in using such compounds as reagents has increased. Marine toxins are some of the most popular research tools and have already contributed much to our understanding of biological processes and disease mechanisms.
First multi-year cumulation covers six years: 1965-70.
Chemoprevention is currently regarded as one of the most promising avenues for the control of cancer, with human epidemiological and animal studies indicating that the risk of cancer may be modified by changes in diet. Over 100 papers are collected in this volume, the proceedings of the International Conference on Food Factors: Chemistry and Cancer Prevention, held in Hamamatsu, Japan, in December 1995. Special emphasis is placed on chemical, biological, and molecular properties of phytochemicals in teas, fruit, vegetables, herbs, and spices, and on their potential for cancer prevention. Also discussed are the cancer-preventive effects of vitamins, lipids, carotenoids, flavonoids, and other components of diet. The findings presented here will be invaluable to all who are interested in diet and cancer prevention, and especially to biochemists, pharmacologists, food scientists, and nutritionists.
This book covers green smoothies, detoxification healing methods, health and healing with chlorophyll foods, the alkaline body, oxygen and related topics. Optimum health and curing is possible through this Living Nutrition, but it is hard work and takes discipline. Our food choices and the way we lead our lives are both the cause and effect of our diet and lifestyle. Our choices reflect the state of harmony with oneself, the world, all of creation, and the Divine. It involves choosing between the "Culture of Life" and the "Culture of Death." This is a pilgrimage from one plateau to another on the Lord's mountain; it is for those desiring to be healthy, happy, and holy in their body, soul and spirit. Jesus said in the beginning of his ministry; "Purify Thyself (or Repent), for the Kingdom of God is at hand!" Biblical Nutrition and Spiritual Nutrition are also explained in this work.