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Uses Computational Tools to Simulate Endocrine Disruption PhenomenaEndocrine Disruption Modeling provides a practical overview of the current approaches for modeling endocrine activity and the related potential adverse effects they may induce on environmental and human health. Based on the extensive research of an international panel of contributor
Microbial toxins are secondary metabolites that accumulate in the organism and, to a large extent, are metabolically inactive towards the organism that produces them. The discovery of penicillin, a secondary metabolite of Penicillium notatum West (= P. chrysogenum Thom), in 1929 marked a milestone in the development of antibiotics (microbial toxins). In the intensive studies that followed this discovery, scientists chemically characterized several new molecules (toxins) from secondary metabolites of microbes, some having a definite function in causing pathogenesis in plants. Toxins are also known to playa significant role in inciting animal (human) and insect diseases and as plant growth reg...
The only comprehensive reference on this popular and rapidly developing technique provides a detailed overview, ranging from fundamentals to applications, including a section on the evaluation of GC-MS analyses. As such, it covers all aspects, including the theory and principles, as well as a broad range of real-life examples taken from laboratories in environmental, food, pharmaceutical and clinical analysis. It also features a glossary of approximately 300 terms and a substance index that facilitates finding a specific application. The first two editions were very well received, making this handbook a must-have in all analytical laboratories using GC-MS.
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Thousands of arthropod species, ranging from arachnids (spiders and scorpions) to hymenopterans (ants, bees, and wasps) and myriapods (centipedes), are venomous and use their venoms for both defense and predation. These venoms are invariably harmful to humans, and some may cause serious injuries, e.g., those from scorpions, spiders, and wasps. Arthropods’ venoms are also known as rich sources of biologically active compounds and have attracted the attention of toxin researchers for years. In this century, venom component analysis has progressed considerable due to the advances in analytical techniques, in particular, mass spectrometry and next-generation deep (DNA and RNA) sequencing. As s...
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