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Endocrine Disruption Modeling
Uses Computational Tools to Simulate Endocrine Disruption PhenomenaEndocrine Disruption Modeling provides a practical overview of the current approaches for modeling endocrine activity and the related potential adverse effects they may induce on environmental and human health. Based on the extensive research of an international panel of contributor
Advances in Microbial Toxin Research and Its Biotechnological Exploitation
Microbial toxins are secondary metabolites that accumulate in the organism and, to a large extent, are metabolically inactive towards the organism that produces them. The discovery of penicillin, a secondary metabolite of Penicillium notatum West (= P. chrysogenum Thom), in 1929 marked a milestone in the development of antibiotics (microbial toxins). In the intensive studies that followed this discovery, scientists chemically characterized several new molecules (toxins) from secondary metabolites of microbes, some having a definite function in causing pathogenesis in plants. Toxins are also known to playa significant role in inciting animal (human) and insect diseases and as plant growth reg...
Arthropod Venom Components and Their Potential Usage
Thousands of arthropod species, ranging from arachnids (spiders and scorpions) to hymenopterans (ants, bees, and wasps) and myriapods (centipedes), are venomous and use their venoms for both defense and predation. These venoms are invariably harmful to humans, and some may cause serious injuries, e.g., those from scorpions, spiders, and wasps. Arthropods’ venoms are also known as rich sources of biologically active compounds and have attracted the attention of toxin researchers for years. In this century, venom component analysis has progressed considerable due to the advances in analytical techniques, in particular, mass spectrometry and next-generation deep (DNA and RNA) sequencing. As s...
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The Comparative Syntax of Korean and Japanese
This book provides a detailed survey of Korean and Japanese syntax from a comparative perspective, based within a generative framework. Yukata Sato and Sungdai Cho demonstrate that while the two languages exhibit remarkably similar morphosyntactic features, they behave differently in specific types of construction, with the main differences observed in genitive marking, sentence negation, Negative Polarity Items, the formation of causatives, and passivization. The book also explores pragmatic and sociolinguistic issues in the two languages, and shows that they differ in the perception and realization of 'givenness' as a topic marker and in the influence of relationships of power and distance on the use of honorifics. The authors further offer additional context by exploring the typological relationship between Japanese and Korean and the surrounding languages such as Ainu, and the Chinese and Altaic languages, as well as providing socio-cultural and historical background.
