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Blue Book
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Sensing, Signaling and Cell Adaptation
In this volume of Cell and Molecular Responses to Stress articles provide up-to-date information on key areas of signal sensing (sensing of pain, heat, cold, light, infrared radiation), molecules involved in the intracellular transmission of these signals, metabolic responses to stress including changes in gene expression and production of specialized proteins that aid cell responses to factors including interrupted blood supply (ischemia), oxygen limitation (hypoxia/anoxia), freezing and dehydration, amino acid limitation, radiation and processing drugs. There are chapters which also provide insights into new technologies (such as cDNA arrays), analysis of metabolic control theory (a key method for analysing stress effects on cells), and examine how enzymes evolve in the face of stress.
Medicinal Chemistry of Nucleic Acids
Complete, up-to-date coverage of the broad area of nucleic acid chemistry and biology Assembling contributions from a collection of authors with expertise in all areas of nucleic acids, medicinal chemistry, and therapeutic applications, Medicinal Chemistry of Nucleic Acids presents a thorough overview of nucleic acid chemistry—a rapidly evolving and highly challenging discipline directly responsible for the development of antiviral and antitumor drugs. This reliable resource delves into a multitude of subject areas involving the study of nucleic acids—such as the new advances in genome sequencing, and the processes for creating RNA interference (RNAi) based drugs—to assist pharmaceutic...
Chloride Transport in Biological Membranes
Chloride Transport in Biological Membranes is a collection of papers that present advances and the state of knowledge in the transport of chloride and other anions across biological membranes. The book includes papers that discuss topics such as the anion transport protein; functional sites of the red cell anion exchange protein; and anion and proton transport through lipid bilayers. Also covered in the book are chloride transport in certain areas such as the renal tubule, the gastric mucosa, and the cornea; the role of sodium in anion transport; chloride reabsorption; and the hormonal control of chloride secretion. The text is recommended for biologists, biochemists, and practitioners in health science, especially those who would like to know more about the processes involved in chloride transport.
Research Grants
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PARP as a Therapeutic Target
Recent research in cell death mechanisms has rekindled interest in PARP's (Poly (ADP-Ribose) Polymerase) intriguing role in necrosis and apoptosis. While the details of how PARP1 functions are still being elucidated, it has tremendous potential as a promising drug target. PARP inhibitors' dual actions of preventing cell death and abating inflammati
Methods in Cell Biology
Critically acclaimed for more than 25 years, the Methods in Cell Biology series provides an indispensable tool for the researcher. Each volume is carefully edited by experts to contain state-of-the-art reviews and step-by-step protocols. Techniques are described completely so that methods are made accessible to users.
Intracellular PH
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Advances in Pharmacology
Each volume of Advances in Pharmacology provides a rich collection of reviews on timely topics. Emphasis is placed on the molecular bases of drug action, both applied and experimental.
