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Learning from Design
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Clinical metagenomics-based diagnostics for infectious diseases
Clinical metagenomics is an emerging method in the diagnosis of infectious diseases that uses next generation sequencing (NGS) technology to identify the etiologic agents to allow for more effective and targeted treatment of infectious diseases. Conventional diagnostic methods are mainly based on basic morphologic, phenotypic and genotypic analyses which can be insensitive and/or time consuming. Metagenomic NGS (mNGS) can be performed with only a small amount of nucleic acid from the specimen and not only can the pathogen be identified and characterized, but also its antimicrobial susceptibility can be inferred. Although tremendous advancements were made in the speed, throughput, and cost of NGS in recent years, the application of clinical metagenomics in routine diagnosis of infectious diseases is not yet practical because of its much higher cost compared to conventional microbiological tests, complex laboratory workflows and computational challenges.
Engineering Web Applications
Nowadays, Web applications are almost omnipresent. The Web has become a platform not only for information delivery, but also for eCommerce systems, social networks, mobile services, and distributed learning environments. Engineering Web applications involves many intrinsic challenges due to their distributed nature, content orientation, and the requirement to make them available to a wide spectrum of users who are unknown in advance. The authors discuss these challenges in the context of well-established engineering processes, covering the whole product lifecycle from requirements engineering through design and implementation to deployment and maintenance. They stress the importance of models in Web application development, and they compare well-known Web-specific development processes like WebML, WSDM and OOHDM to traditional software development approaches like the waterfall model and the spiral model. .
Web Intelligence: Research and Development
This book constitutes the refereed proceedings of the First Asia-Pacific Conference on Web Intelligence, WI 2001, held in Maebashi City, Japan, in October 2001.The 28 revised full papers and 45 revised short papers presented were carefully reviewed and selected from 153 full-length paper submissions. Also included are an introductory survey and six invited presentations. The book offers topical sections on Web information systems environments and foundations, Web human-media engineering, Web information management, Web information retrieval, Web agents, Web mining and farming, and Web-based applications.
Boron Nitride Nanostructures Special Issue Editors Philippe Miele Mikhael Bechelany MDPI •
This book is a printed edition of the Special Issue "Boron Nitride Nanostructures" that was published in Nanomaterials
Interactivation
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Electronic Business and Education
In order to establish technical prerequisites for efficient electronic business and education on the Internet, appropriate system support is needed as a vital condition for maximization of both short-term and long-term profits. Electronic Business and Education: Recent Advances in Internet Infrastructures discusses current research topics in the domain of system support for e-business and e-education on the Internet, and stresses the synergistic interaction of these two components. Attention is given to both scientific and engineering issues. Electronic Business and Education: Recent Advances in Internet Infrastructures is suitable as a secondary text for a graduate level course and as a reference for researchers and practitioners in industry, particularly in the area of e-business and e-education on the Internet. `There is no longer any question that the Internet and electronic communication are the major new tools for collaborative advances in the creation of new knowledge and in future learning.' Excerpt from Foreword by Robert C. Richardson, Nobel Laureate 1996, Cornell University, USA
