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Genes, Development and Cancer
- For the first time, Nobel Prize winner, Edward B. Lewis' research papers are published within one volume - Papers are organized into sections that reflect the focus of the research - Commentaries by Howard Lipshitz highlight key methods and results by explaining the science so it is accessible to upper-level undergraduates, graduate students, and professional researchers
The Maternal-to-Zygotic Transition
The Maternal-to-Zygotic Transition provides users with an expert accounting of the mechanisms and functions of this transition in a range of animal and plant models. The book provides critical information on how maternal gene products program the initial development of all animal and plant embryos, then undergoing a series of events, termed the maternal-to-zygotic transition, during which maternal products are cleared and zygotic genome activation takes over the developmental control. - Maternal gene products program the initial development of all animal and plant embryos - These then undergo a series of events, termed the maternal-to-zygotic transition, during which maternal products are cleared and zygotic genome activation takes over developmental control - In this book, experts provide their insights into the mechanisms and functions of this transition in a range of animal and plant models.
Advances in Developmental Biology
Volume 4 of Advances in Developmental Biology and Biochemistry consists of five chapters that review specific aspects of fly and mammalian development. In Chapter 1, Y. Mishina and R. Behringer discuss various aspects of Müllerian-inhibiting substance (MIS) in mammals, from a brief history of its discovery to recent studies of the MIS gene in transgenic and knock-out animals. In Chapter 2, C. Rushlow and S. Roth discuss the role of the dpp-group genes in dorsoventral patterning of the Drosophila embryo. In Chapter 3, M. Yip and H. Lipshitz discuss the terminal (asegmental termini) gene hierarchy of Drosophila and the genetic control of tissue specification and morphogenesis. In Chapter 4, R. Bachvarova discusses induction of mesoderm and the origin of anterior-posterior polarity in the mouse embryo, using the frog embryo as a paradigm. In Chapter 5, P. Vogt discusses human Y chromosome function in male germ cell development.
Principles of Developmental Genetics
Unlike anything currently available in the market, Dr. Sally A. Moody and a team of world-renowned experts provide a groundbreaking view of developmental genetics that will influence scientific approaches in embryology, comparative biology, as well as the newly emerging fields of stem cell biology and regenerative medicine. Principles of Developmental Genetics highlights the intersection of developmental biology with new revolutionary genomic technologies, and details how these advances have accelerated our understanding of the molecular genetic processes that regulates development. This definitive resource provides researchers with the opportunity to gain important insights into the clinica...
Localized RNAs
This book is about the mechanisms by which certain RNAs are localized in cells and the functions of such localized RNAs. The first of this kind, this volume presents a current survey of this young field, and brings together chapters on each of the key experimental systems. These include studies on Drosophila and Xenopus oocytes such as fibroblasts, myoblasts, glial cells and neurons. In each case, leading authorities present the conceptual and technical background to their studies, and then survey the mechanisms and functions of localization of particular RNAs.
Developmental Biology
This work examines rules, system properties and mechanisms underlying developmental gene regulation in a broad range of organisms. It covers the thoughts and theories, experimental inventions, strategies and successes of recent investigations into developmental processes in organisms ranging from yeast and fungi to higher eucaryotes. Some of the specific topics covered include: calcium, cell cycle control, the role of protein kinase
