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Manslaughter United
People don't want to know us. They don't want to know we exist. We have all committed horrendous crimes, and they aren't going to understand why we're allowed to play football. But it's the only thing that makes our lives bearable. We play in a local league - home games only - and it doesn't matter then who you are or what you've done, you can still be a hero on match day. For those ninety minutes it's your FA Cup, your European Cup, your World Cup. Zebedee, Teddy, Bunny, Nigel, Scouse, Raph, Bumpy, Wayne, Carl, Paddy and Rizler. Eleven men - a football team. In every British town there are hundreds of amateur football teams. This team has the usual sprinkling of talent, but is otherwise unique. Nine of these players have been convicted of murder and are serving life-sentences in HMP Kingston, the other two are their warders. Chris Hulme spent a season with the Kingston Arrows - watching every game, talking to them about their lives on the inside and out and supporting them in their attempt to win the league for the first time in ten years of trying. MANSLAUGHTER UNITED - the story of the hardest football team in England.
Small Molecule Medicinal Chemistry
Stressing strategic and technological solutions to medicinal chemistry challenges, this book presents methods and practices for optimizing the chemical aspects of drug discovery. Chapters discuss benefits, challenges, case studies, and industry perspectives for improving drug discovery programs with respect to quality and costs. • Focuses on small molecules and their critical role in medicinal chemistry, reviewing chemical and economic advantages, challenges, and trends in the field from industry perspectives • Discusses novel approaches and key topics, like screening collection enhancement, risk sharing, HTS triage, new lead finding approaches, diversity-oriented synthesis, peptidomimetics, natural products, and high throughput medicinal chemistry approaches • Explains how to reduce design-make-test cycle times by integrating medicinal chemistry, physical chemistry, and ADME profiling techniques • Includes descriptive case studies, examples, and applications to illustrate new technologies and provide step-by-step explanations to enable them in a laboratory setting
Multicomponent Reactions
In the very first book on this hot topic, the expert editors andauthors present a comprehensive overview of these elegantreactions. From the contents: Organoboron compounds Free-radical mediated multicomponent coupling reactions Applications in drug discovery Metal catalyzed reactions Total synthesis of natural products Asymmetric isocyanide-based reactions The Biginelli reaction Asymmetric isocyanide-based reactions The Domino-Knoevenagel-Hetero-Diels-Alder Reaction and relatedtransformations Catalytic asymmetric reactions Algorithm based methods for discovering novel reactions Post-condensation modifications of the Passerini and Ugireactions An essential reference for organic and catalytic chemists, andthose working in organometallics both in academia and industry.
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Isocyanide Chemistry
The efficacy of isocyanide reactions in the synthesis of natural or naturallike products has resulted in a renaissance of isocyanide chemistry. Now isocyanides are widely used in different branches of organic, inorganic, coordination, combinatorial and medicinal chemistry. This invaluable reference is the only book to cover the topic in such depth, presenting all aspects of synthetic isonitrile chemistry. The highly experienced and internationally renowned editor has brought together an equally distinguished team of authors who cover multicomponent reactions, isonitriles in total synthesis, isonitriles in polymer chemistry and much more.
Connectionist Models of Memory and Language (PLE: Memory)
Connectionist modelling and neural network applications had become a major sub-field of cognitive science by the mid-1990s. In this ground-breaking book, originally published in 1995, leading connectionists shed light on current approaches to memory and language modelling at the time. The book is divided into four sections: Memory; Reading; Computation and statistics; Speech and audition. Each section is introduced and set in context by the editors, allowing a wide range of language and memory issues to be addressed in one volume. This authoritative advanced level book will still be of interest for all engaged in connectionist research and the related areas of cognitive science concerned with language and memory.
Working Memory in Perspective
The Baddeley and Hitch (1974) Working Memory model holds a central place in experimental psychology and continues to be extremely successful in guiding and stimulating research in applied and theoretical domains. Yet the model now faces challenges from conflicting data and competing theories. In this book, experienced researchers in the field address the question: Will the model survive these challenges? They explain why it is so successful, evaluate its weaknesses with respect to opposing data and theories and present their vision of the future of the model in their particular area of research. The book includes a discussion of the "Episodic Buffer" component which has recently been added t...
The Oxford Handbook of Reading
Writing is one of humankind's greatest inventions, and modern societies could not function if their citizens could not read and write. How do skilled readers pick up meaning from markings on a page so quickly, and how do children learn to do so? The chapters in the Oxford Handbook of Reading synthesize research on these topics from fields ranging from vision science to cognitive psychology and education, focusing on how studies using a cognitive approach can shed light on how the reading process works. To set the stage, the opening chapters present information about writing systems and methods of studying reading, including those that examine speeded responses to individual words as well as ...
