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Principles of Stem Cell Biology and Cancer: Future Applications and Therapeutics Tarik Regad, The John van Geest Cancer Research Centre, Nottingham Trent University, UK, Thomas J. Sayers, Centre for Cancer Research, National Cancer Institute, Frederick, USA and Robert Rees The John van Geest Cancer Research Centre, Nottingham Trent University, UK The field of cancer stem cells is expanding rapidly, with many groups focusing on isolating and identifying cancer stem cell populations. Although some progress has been made developing efficient cancer therapies, targeting cancer stem cells remains one of the important challenges facing the growing stem cell research community. Principles of Stem C...
First multi-year cumulation covers six years: 1965-70.
Abstract: The proceedings of a 1980 workshop presents 19 expert papers on various aspects of the effect of alcohol (ethanol) intake on in vivo protein biosynthesis. The papers are grouped among 3 principal themes: 1) the effects of alcohol on the biosynthesis of brain protein and nucleic acid macromolecules; 2) the effects of ethanol on eukaryotic protein biosynthesis; and 3) biobehavioral and cellular studies on ethanol effects. The adverse consequences of maternal alcoholism on fetal protein metabolism and the neurological aspects and complications of alcoholism also are addressed. (wz).
The power of stem cells for tissue development, regeneration, and renewal has been well known by embryologists and developmental biologists for many years. Those presently active in research in the stem cell field owe much to previous work by embryologists and cancer researchers for their insights into what stem cells can do. In the last 4- 5 years, the rapid expansion of the concept of adult tissue stem cells as pluripotent progenitors for various tissues has led to an even greater appreciation of the power of stem cells. The demonstration that both embryonic and adult tissue stem cells have the ability to produce progenitor cells for tissue renewal has opened vast possibilities for treatme...