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Ovarian cancer provides an up-to-date and comprehensive synthesis of clinical management and research progress in the field of epithelial ovarian cancer. The book has its origins in two separate but complementary initiatives. One initiative was a series of reviews commissioned to cover thespectrum of clinical management of ovarian cancer from prevention, screening and diagnosis to surgery, chemotherapy and palliative care. The reviews were invited from an international panel of clinicians with expertise in the management of ovarian cancer. The second initiative was co-ordinated bythe Helene Harris Memorial Trust (HHMT) which has organised key biennial meetings on ovarian cancer for the last ...
Providing a thorough and up-to-date overview of the full range of gynaecological cancers, Gynaecological Oncology is a concise introduction, particularly useful for trainees working towards postgraduate examinations. The first section includes introductory chapters on epidemiology, screening and prevention, imaging, pathology, surgery, radiation therapy, chemotherapy, and palliation. The second part of the book covers the gynaecological cancer types in turn; each chapter following a similar format looking at clinical issues, staging, and principles of management. Where appropriate, flow-charts and diagrams are used to help the reader assimilate complex information. A chapter is devoted to decision-making, addressing those issues clinicians and women face when deciding on optimal management in given clinical scenarios. The book is practically based and is enhanced by highlighting learning points, management algorithms and clinical images. This is an invaluable resource for all doctors and allied health professionals dealing with women with gynaecological cancers.
If there is one aspect of current cancer research that represents a major ch- lenge in both novice and experienced researchers, it is the rapid advance in our understanding of the disease. Researchers can be required to switch from analysis of gene expression to kinetics of protein activation, from genetic studies to the analysis of protein funtion. Cancers are highly complex disease systems and researchers aiming to understand the functioning of cancer systems require access to a wide range of laboratory techiques from a broad range of research disciplines. Increasingly, however, published methods are incomplete or refer back to a series of previous publications each containing only a small...
While there are a plethora of practical texts relating to general gynecology, there are few specific to gynecological oncology. Taking a "cookbook" approach with clearly written and pictorial instructions, Atlas of Gynecologic Oncology: Investigation and Surgery describes and illustrates important procedures in the repertoire of a gynecological oncologist. International authorities contribute their expertise on a range of topics, including tumor markers, pain management, cross-sectional imaging, treatment of vascular defects, and more. The book pulls together investigations performed by the authors and their colleagues from other disciplines. It covers computed tomography, magnetic resonance...
Long recognized as the standard general reference work providing a complete overview of contemporary gynaecological practice, this new edition of Shaw, Gynaecology provides all the information that trainees need to master in order to successfully take their professional certification exams as well as providingthe practicing gynaecologist with an accessible overview of the "state of play" of diagnostic and therapeutic procedures. Totally rewritten, it gives a succinct but comprehensive account of all currently available resources in the management of gynaecological disorders. Comprehensive overview of contemporary gynaecological practice with a clinically focused approach. It covers all of th...
Many human genetic diseases associated with blood, brain, colon, ear, eye, heart, kidney, liver, muscle, and pancreas are caused by mutations in mitochondrial DNA. Mutations in DNA can result in defects of the electron transport complexes, intermediates of the tricarboxylic acid cycle and substrate transport. The clinical manifestation of these diseases often involves muscle and the nervous system. Mitochondrial DNA mutations have now been associated with aging as well as age-related degenerative diseases such as Parkinson's, Alzheimer's, and Huntington's diseases. Changes in structure, function, and a number of mitochondria play an important role in carcinogenesis. Furthermore, the role of mitochondria in the execution of programmed cell death or apoptosis has been recognized recently.
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"Summaries of papers" contained in the journal accompany each issue, 19--