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A presentation of all aspects of neural crest cell origins (embryological and evolutionary) development and evolution; neural crest cell behavior (migration) and anomalies (neurocristopathies and birth defects) that arise from defective neural crest development. The treatment of development will include discussions of cellular, molecular and genetic aspects of the differentiation and morphogenesis of neural crest cells and structures derived from neural crest cells. The origins of the neural crest in embryology will be discussed using the recent information on the molecular basis of the specification of the neural crest. Also presented are the advances in our understanding of the evolution of jaws from studies on lampreys and of the neural crest from studies on ascidians and amphioxus.
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This 1999 edition of The Neural Crest contains comprehensive information about the neural crest, a structure unique to the vertebrate embryo, which has only a transient existence in early embryonic life. The ontogeny of the neural crest embodies the most important issues in developmental biology, as the neural crest is considered to have played a crucial role in evolution of the vertebrate phylum. Data that analyse neural crest ontogeny in murine and zebrafish embryos have been included in this revision. This revised edition also takes advantage of recent advances in our understanding of markers of neural crest cell subpopulations, and a full chapter is now devoted to cell lineage analysis. The major research breakthrough since the first edition has been the introduction of molecular biology to neural crest research, enabling an elucidation of many molecular mechanisms of neural crest development. This book is essential reading for students and researchers in developmental biology, cell biology, and neuroscience.
Comparative Neuropathology focuses on documented accounts of neurologic diseases and congenital defects in animals. The book first offers information on neuropathology, neuroanatomy, and cerebrospinal fluid (CSF). The domesticated animals that have CSF include horses, dogs, pigs, cats, rabbits, and cattle. The text then elaborates on neurologic diseases of apes and monkeys. Discussions focus on confluent leucoencephalosis and perivascular myelosis, encephalopathies and dysenteric syndromes, meningitis, epilepsies, tuberculosis, cerebellar atrophy and experimental manganese poisoning, and choreic syndrome in baboons with corticostriate encephalitis. The publication examines the diseases of the skeletal muscle and hypophysis, including general reactions of muscles to injuries, congenital defects, muscular dystrophies, changes in muscle associated with specific diseases, and tumor. The manuscript also takes a look at inherited diseases and congenital anomalies, protozoan and bacterial infections, and demyelinating or myelinoclastic diseases. The text is a dependable reference for readers interested in comparative neuropathology.
Neurodevelopmental disorders arise from disturbances to various processes of brain development, which can manifest in diverse ways. They encompass many rare genetic syndromes as well as common, heritable conditions such as intellectual disability, autism, ADHD, schizophrenia and many types of epilepsy. The Genetics of Neurodevelopmental Disorders examines recent revolutionary advances in our understanding of the genetics of these disorders, exploring both basic discoveries and the translation of new findings into the clinical setting. The book begins by examining the genetic architecture and etiology of neurodevelopmental disorders. It describes the striking recent progress in identifying pa...
The book provides insight on the osteology, myology, phylogeny and evolution of Osteichthyes. It not only provides an extensive cladistic analysis of osteichthyan higher-level inter-relationships based on a phylogenetic comparison of 356 characters in 80 extant and fossil terminal taxa representing all major groups of Osteichthyes, but also analyses various terminal taxa and osteological characters. And also provides a general discussion on issues such as the comparative anatomy, homologies and evolution of osteichthyan cranial and pectoral muscles, the development of zebrafish cephalic muscles and the implications for evolutionary developmental studies, the origin homologies and evolution of one of the most peculiar and enigmatic structural complexes of osteichthyans, the Weberian apparatus, and the use of myological versus osteological characters in phylogenetic reconstructions.