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Bacterial Exotoxins: How Bacteria Fight the Immune System
Bacterial pathogenicity factors are functionally diverse. They may facilitate the adhesion and colonization of bacteria, influence the host immune response, assist spreading of the bacterium by e.g. evading recognition by immune cells, or allow bacteria to dwell within protected niches inside the eukaryotic cell. Exotoxins can be single polypeptides or heteromeric protein complexes that act on different parts of the cells. At the cell surface, they may insert into the membrane to cause damage; bind to receptors to initiate their uptake; or facilitate the interaction with other cell types. For example, bacterial superantigens specifically bind to major histocompatibility complex (MHC) II mole...
Ñusta: the Inka love of Francisco Pizarro
Dr. Rafael Olivares uses historical fiction to transcribe the recently found personal diary of Ñusta Yupanqui. The daughter and sister of Inkas, Ñusta was also the lover of Francisco Pizarro, the conqueror of Peru. Although she was an Inka princess and gave Pizarro the only children he ever had, the official history of the Spanish conquest ignores her. This novel suggests that, because she was in the middle of the struggle, the successes described in the diary could be the real history of the Spanish domination of the Inka Empire. Ñusta’s narrative not only presents the historical interpretation of the conquest as seen by the defeated but also reveals the existence of a treasure still hidden in the Andes Mountains. This Inka treasure is bigger than anything found until now.
Foodborne Bacterial Pathogens
Bacteria are estimated to cause some 24 million cases of diarrheal disease annually in the US. These papers have wide importance providing background information and recent research findings and giving a comprehensive, current understanding of bacterial pathogens associated with foods and their role
Clinical Epigenetics
In genetic pathology, epigenetic testing is rare and under utilised. In this book, we introduce epigenetics to a non-expert scientific audience and describe current and future clinical utility of epigenetic testing. By focussing on epigenetics in human disease this book will guide professionals (scientists and clinicians) to understand how epigenetics is relevant in a clinical context, and to implement epigenetic testing in diagnostic laboratories. The book begins with a historical perspective of genetics and epigenetics and describes the work of pioneers who have helped shape these fields. The various mechanisms by which epigenetics can regulate the function of the genome is described. Thes...
The Diverse Faces of Bacillus Cereus
The Diverse Faces of Bacillus cereus elucidates all characteristics of this microorganism, from its environmental and ecologic relevance, to its veterinary involvement, its clinical settings, most common B. cereus associated food poisoning episodes, and the newest airway disease pictures mimicking the inhalation of anthrax. Due to its environmental distribution, B. cereus may cause serious, even fatal human diseases. The organism shows many diverse faces, as it is not only a veterinary pathogen, but also used as a biocontrol agent to control vegetable decay due to its natural antimicrobial properties. Once considered as a mere colonizer or contaminant, Bacillus cereus is nowadays acquiring i...
Primary Immunodeficiency Disorders
Primary Immunodeficiency Disorders: A Historic and Scientific Perspective provides a complete historical context that is crucial for students and researchers concerned with primary immunodeficiency. When researchers have a poor understanding of the way we arrived where we are in research, they can miss important points about a disease, or miss out on how to approach new diseases. This historical knowledge of research can assist greatly by showing how it was done in the past, demonstrating the successes and failures, so that it can be done better in the future. This book provides an understanding of the process going from clinical problem to lab and back to the clinic, based on historical exp...
Clinical Respiratory Medicine
This comprehensive clinical textbook examines all aspects of respiratory medicine. The editors take a practical approach to the diagnosis and management of patients with the full range of pulmonary disorders, making this your ideal source for reference in clinical practice. Fully revised, this essential volume includes new chapters on PET imaging, implications of genetic research, oxygen therapy, and rehabilitation. Now an Expert Consult title, it comes with access to the complete contents of the book online, including all of the book’s images, downloadable for use in presentations. Provides complete clinical coverage so you can Better manage and treat patients with pulmonary disease. Uses...
4 "Bauhausmädels"
4 Bauhausmadels Gertrud Arndt, Marianne Brandt, Margarete Heymann, Margaretha Reichardt Edited by Angermuseum Erfurt; Kai Uwe Schierz; Patrick Rossler; Miriam Krautwurst; Elizabeth Otto March 2019 978-3-95498-459-6 u 38 Hardback u 336pp u 275 x 220mm u 496 pictures In 1919, the program of the State Bauhaus promised a modern education for the talented, regardless of age and gender, which drew many young women to apply. The Bauhaus-Girl Type, described in a January 1930 issue of the magazine The Week, knew what she wanted and would succeed. This volume's essays question the euphoria of the time period with the knowledge of Bauhaus members' subsequent destinies. These essays take as exemplary the biographies of Gertrud Arndt, Marianne Brandt, Margarete Heymann, and Margaretha Reichardt, both during their training and as Bauhaus graduates.
