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The most efficient way to mount a sustained immune response is to target antigens to antigen presenting cells that trigger both innate and adaptive immune responses. A comprehensive view of the current approaches to the design of new antigenic formulations will enhance our understanding and perspective of targeted immunotherapy. The aim of this Research Topic is to provide an overview of the currently adopted targeting strategies by a collection of articles on: 1.Novel approaches of antigen targeting for immunotherapeutic strategies against cancer and/or infectious diseases. 2. Diversity and biology of dendritic cell subsets in human and mouse. 3. Combined strategies for the delivery of antigens and adjuvant molecules that stimulate innate immune responses and their influence on the quality of immune responses. 4. Impact of the receptor mediate intracellular trafficking on antigen presentation.
MEMORIA: An Anthology of Portuguese Canadian Writers showcases contemporary fiction, nonfiction and poetry that reflect the changing Portuguese Canadian community while supporting new voices in the diaspora. Contributors include Clemente Alves, Edith Baguinho, Nelia Botelho, Esmeralda Cabral, Tony Correia, paulo da costa, Humberto da Silva, Aida Jordão, Irene Marques, Antonio M. Marques, Emanuel Melo, Eduardo Bettencourt Pinto, Paul Serralheiro, Richard Simas, and Laureano Soares. Foreword by noted academic and author Onésimo T. Almedia.
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In our hyper-connected digital world, cybercrime prevails as a major threat to online security and safety. New developments in digital forensics tools and an understanding of current criminal activities can greatly assist in minimizing attacks on individuals, organizations, and society as a whole. The Handbook of Research on Digital Crime, Cyberspace Security, and Information Assurance combines the most recent developments in data protection and information communication technology (ICT) law with research surrounding current criminal behaviors in the digital sphere. Bridging research and practical application, this comprehensive reference source is ideally designed for use by investigators, computer forensics practitioners, and experts in ICT law, as well as academicians in the fields of information security and criminal science.
Antibiotic-resistant bacterial strains remain a major global threat, despite the prevention, diagnosis and antibiotherapy, which have improved considerably. In this thematic issue, the scientists present their results of accomplished studies, in order to provide an updated overview of scientific information and also, to exchange views on new strategies for interventions in antibiotic-resistant bacterial strains cases and outbreaks. As a consequence, the recently developed techniques in this field will contribute to a considerable progress in medical research.
This collection of papers presents different views on metaphor in communication. The overall aim is to show that the communicative dimension of metaphor cannot be reduced to its conceptual and/or linguistic dimension. The volume addresses two main questions: does the communicative dimension of metaphor have specific features that differentiate it from its linguistic and cognitive dimensions? And how could these specific properties of communication change our understanding of the linguistic and cognitive dimensions of metaphor? The authors of the papers collected in this volume offer answers to these questions that raise new interests in metaphor and communication.
Today, in the face of resistant microorganisms, aggressive cancers unresponsive to conventional treatments, and the COVID-19 pandemic, the need for advanced and innovative protocols for combating and treating disease is paramount. This book presents basic concepts of photodynamic therapy along with data from clinical research on its use in treating oncologic and other diseases. It also presents innovative strategies in photodynamic therapy, including information on polymer nanoparticles. This book was prepared with great care and by many valuable hands so that we can expand the dissemination of Photodynamic Therapy, as well as motivate for new research.