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Primary Immunodeficiencies Worldwide
  • Language: en
  • Pages: 224
Pediatric Immunology
  • Language: en
  • Pages: 792

Pediatric Immunology

This book comprises a collection of categorized case-based questions, directed and meticulously selected to cover the most common and most important aspects of immunodeficiency diseases. Immunodeficiency disorders of infancy and childhood such as antibody deficiencies, phagocyte defects and defects in innate immunity are addressed among others. Each chapters starts with a brief of the initial presentation and lab data of the patient, followed by a series of 5-6 multiple choice questions (MCQs), leading the reader to the diagnosis and best of practice in a step-wise manner. This MCQ format along with precise, yet detailed answer ensures a quick, case-based, reality learning to the reader. This comprehensive MCQ series, is an essential reading material that a pediatric clinician, hematologist, immunologist, transplant specialist, or pulmonologist, can not afford to miss.

Advances in Primary Immunodeficiency in Central-Eastern Europe
  • Language: en
  • Pages: 124
Computational and Experimental Protein Variant Interpretation in the Era of Precision Medicine
  • Language: en
  • Pages: 146

Computational and Experimental Protein Variant Interpretation in the Era of Precision Medicine

One of the key goals in the postgenomic era is the elucidation of the mechanisms underlying the relationship between genotype and phenotype. In particular, understanding how human genetic and somatic variations are associated with diseases is still an open problem and its solution is a crucial issue for exploiting the possibilities offered by the modern sequencing techniques in the framework of precision and personalized medicine. The increasing amount of data generated by the sequencing initiatives calls for accurate and reliable computational approaches to predict the impact of mutations on the phenotype, and possibly for methods to correlate them with diseases. From the experimental point of view, disease-causing variants are supposed to directly affect protein function, protein stability as well as the kinetics and thermodynamics of protein-protein recognition, and robust validation at the molecular scale is necessary. This approach can be of invaluable help in facing new challenges such as the fast development of effective vaccines.

Machine Learning Techniques on Gene Function Prediction
  • Language: en
  • Pages: 485
Göytepe: Neolithic Excavations in the Middle Kura Valley, Azerbaijan
  • Language: en
  • Pages: 386

Göytepe: Neolithic Excavations in the Middle Kura Valley, Azerbaijan

This volume publishes the first round of fieldwork and research (2008-2013) at Göytepe, a key site for understanding the emergence and development of food-producing communities in the South Caucasus. Results include findings relating to chronology, architecture, technology, social organisation, plant and animal exploitation, and more.

Trained Immunity-based Vaccines
  • Language: en
  • Pages: 195

Trained Immunity-based Vaccines

Dr. Jose Luis Subiza is the founder and CEO of Inmunotek SL. The other Topic Editors declare no competing interests with regard to the Research Topic subject.

Evidence-based Practice in the Early Childhood Field
  • Language: en
  • Pages: 284

Evidence-based Practice in the Early Childhood Field

  • Type: Book
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  • Published: 2006
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  • Publisher: Unknown

The concept of evidence-based practice is helping early educators, special educators, early interventionists, child care professionals, mental health professionals, social workers, health-care professionals, and others work together more effectively to transform the services provided to children and families. This unique book defines the evidence-based practice movement and explains how it is empowering professionals to deliver the most effective interventions available. The authors examine how evidence-based practice is changing the way research is conducted, how research findings can be applied to solve real-world problems, and how research can be used to inform critical policy decisions.

Interventions in Pulmonary Medicine
  • Language: en
  • Pages: 639

Interventions in Pulmonary Medicine

  • Type: Book
  • -
  • Published: 2017-11-21
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  • Publisher: Springer

This new edition offers comprehensive coverage of all areas of interventional pulmonology, a minimally invasive endoscopic method for diagnosing and treating lung disorders. The text is divided into eight sections on the major areas of interventional pulmonology, including basic endoscopy, lung cancer staging, and interventional bronschoscopy in asthma and emphysema. Chapters then explore specific procedures and techniques, including medical thoracoscopy, flexible and rigid bronchoscopy, endobronchial ultrasound, and electromagnetical navigation with coverage of history, indications and contraindications, and up-to-date evidence-based reviews. In recent years there have been many advances in...