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Salivary Glands
Salivary glands are of utmost importance for several physiological functions ranging from the protection of teeth and surrounding soft tissues to the lubrication of the oral cavity, which is crucial for speech and perception of food taste. This publication highlights specific aspects of salivary gland development, investigating the mechanisms involved in embryonic development, the current research in stem cells, the ability of adult glands to regenerate and the signalling pathways involved in this process. Key stages of salivary gland development, moving from initiation to differentiation of the glands, are discussed, as well as unusual adaptations, ranging from making silk to making venom. The book finally provides new data on surgical techniques and diagnostic tools for clinicians involved in salivary gland disorders. Researchers and students with an interest in craniofacial sciences as well as clinicians dealing with salivary gland disorders will find this publication an excellent source of up-to-date information.
Fetal Therapy
Covers the latest insights in fetal therapy and provides essential knowledge for maternal-fetal and neonatology specialists.
Signaling Pathways in Developing and Pathological Tissues and Organs of the Craniofacial Complex
Head formation requires the well-orchestrated and harmonised development of various tissues and organs within the craniofacial complex. A big variety of signaling pathways are involved in this process by controlling cell proliferation, migration, differentiation, tissue morphogenesis, homeostasis and regeneration. Deregulation and malfunction of these signaling molecules may lead to mild or severe craniofacial pathologies. This eBook is a collection of articles dealing with a variety of important signals involved in the control of developmental and pathological events of craniofacial organs and tissues. These recent advances show the importance of signaling pathways in craniofacial physiology and pathology and generate important new knowledge aiming the development of new pharmaceutical products that mimic and/or block the actions of specific molecules.
Fundamentals of Oral Histology and Physiology
Fundamentals of Oral Histology and Physiology is a landmark new text streamlining the essentials of histology and physiology into one clinically accessible textbook. Written for predoctoral dental students, the book brings together structure, function, and clinical correlations for maximum retention and ease of use. Assuming a background in basic biologic sciences, this text focuses on the histology and physiology that students need to know to practice dentistry and to understand and evaluate the current literature, without repeating basic information learned in other courses. Fundamentals of Oral Histology and Physiology concentrates on Oral Structures and Features, including Development, Teeth, Tooth and Jaw Support, Mucosal Structure and Function, and Effectors.
Shh and Gli Signalling in Development
This book reviews and summarizes the current state of understanding of the Sonic Hedgehog (shh) pathway and the downstream Gli transcription factors during development. An introductory chapter reviews the pathway both in invertebrates and vertebrates. Subsequent chapters deal with the role of Shh during the development of specific organs and body systems in a variety of organisms including zebrafish, mouse and human.
Science
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REGULATION DES VOIES DE TRANSDUCTION DE SIGNAL PAR LA PROTEINE A BOITE F SLIMB AU COURS DU DEVELOPPEMENT DE DROSOPHILA MELANOGASTER
DURANT MA THESE, J'AI CLONE LE GENE SLIMB (SLMB) ET ETUDIE SON ROLE DANS PLUSIEURS PROCESSUS DEVELOPPEMENTAUX DE LA DROSOPHILE : LA MORPHOGENESE DE LA PATTE ET DE L'AILE, LA MORPHOGENESE DU CERVEAU LARVAIRE, ET L'OVOGENESE CHEZ LA FEMELLE ADULTE. SLMB CODE UNE PROTEINE A BOITE F ET REPETITIONS WD-40 QUI PARTICIPERAIT AUX COMPLEXES MULTIPROTEIQUES SCF IMPLIQUES DANS LE CIBLAGE DE PROTEINES VERS LA VOIE DE DEGRADATION DU PROTEASOME DEPENDANT DE L'UBIQUITINE. JIANG ET STRUHL (1998) ONT MONTRE, AVEC DES ALLELES SLMB FAIBLES, QUE SLMB REGULE NEGATIVEMENT LES VOIES DE SIGNALISATION DE HEDGEHOG (HH) ET WINGLESS (WG). J'AI GENERE PLUSIEURS ALLELES SLMB AMORPHES QUI M'ONT PERMIS DE MONTRER QU'EN PLUS...
Circular Series A.
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