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Advances in Radiotherapy for Head and Neck Cancer
Modern Radiotherapy (RT) plays a key role in the management of Head and Neck Cancer (HNC). More precise delivery techniques, advanced image-guidance, and adaptive treatments characterize modern RT, enabling safer treatments with enhanced therapeutic window. Although patients identify the cure as their most important treatment outcome, complications related to treatment are a recognized problem as follow-up increases among those cured within this oncologic setting. This is particularly relevant for HPV-related oropharyngeal cancer (OPSCC), as these patients are younger, healthier, and more reactive to treatment. Thus, given the longer life expectancy, the jeopardizing impact of side effects on quality of life (QoL) and psychosocial functioning represent a forefront topic for HNC Researchers. De-escalation protocols have been developed recently, and, although not definitive, evidence is growing. This pertains particularly, but not exclusively, to HPV-related OPSCC.
Breast Cancer Radiation Therapy
The book provides, in a comprehensive yet concise way, essential information to improve the knowledge and skills of all healthcare providers involved in the treatment of patients with breast cancer. The content does not focus on general information that is widely available via different sources, but on technical aspects – “hands-on” daily practices and principles of radiation oncology that are not included in other books. Drawing on information taught in courses at e.g. the ESTRO School, as well as the authors’ broad clinical experience, the respective contributions reflect and share the expertise of leading experts in breast cancer radiation therapy, supported by sound data and evidence. Each chapter includes a short introduction summarizing the evidence in the literature and “pearls” (a short bullet-point summary), and is enriched by tables, figures and illustrations to provide a concise, easy-to-follow and appealing overview. The book, containing also useful electronic supplementary material, will be of interest to a wide range of readers, including radiation oncologists, radiation technicians, medical physicists, and others involved in breast cancer care.
Radiobiology of Glioblastoma
This text properly considers the most recent and relevant advances in molecular RB of GB, taking into account the related topics of pathobiology, and underscores the most promising translational perspectives from the preclinical to the clinical domain. Section I (From Bedside to Bench) discusses conditions associated with RT resistance of GB and the consequent RB hints, technology improvements intended to overcome RT-resistance of GB, mathematical modeling of RB parameters from clinical studies, the present impact of molecular prognostic factors in therapy of GB, and RT tolerance of normal brain. Section II (Preclinical Research and Pathobiology Topics) presents the traditional and mechanist...
Oncoplastia e Reconstrução Mamária
A segunda edição de Oncoplastia e Reconstrução Mamária, além de contribuir para a divulgação do conhecimento de técnicas para os profissionais da Medicina, também representa a importância dessa complexa engrenagem que é o tratamento do câncer de mama e das diversas outras necessidades cirúrgicas de pacientes, independentemente da especialidade médica.
Misteri del Libro della Genesi
Questo libro offre una visione intrigante del primo dei “Cinque Libri di Mosè”, la Genesi, aprendo la strada a una comprensione più ampia dei testi biblici. Attraverso uno studio meticoloso, si rivela che i racconti della creazione nella Genesi potrebbero non essere originali, ma piuttosto un'edizione di antiche leggende provenienti da diverse culture, compilate in forma allegorica da Mosè. Il libro mette anche in discussione le traduzioni convenzionali del testo ebraico in inglese, portando alla luce interpretazioni che allineano il racconto biblico con le scoperte della geologia moderna. Ciò è illustrato dal modo in cui le versioni più accurate del testo originale divergono signi...
