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As was shown in the first two volumes of this series, great strides have been made in identifying many of the agents or classes of substances responsible for carcinogenesis and in delineating their interactions with the cell. Clearly, the aim of such studies is that, once identified, these agents can be eliminated from the environment. Yet, despite these advances and the elimination of some important carcinogenic agents, one major problem exists. It is a constant monitor of all oncologic study and diminishes the importance of every experiment and of every clinical observation. As we noted earlier, that problem is our inability to define the malignant cell. It is through studies of the fundam...
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First multi-year cumulation covers six years: 1965-70.
Novel Approaches to Cancer Chemotherapy compiles theories in tumor biology, emphasizing their potential use in developing therapeutic approaches to cancer therapy. This book emphasizes the unique property of a cancer cell and describes in detail how a novel therapeutic approach can be developed. This compilation consists of 11 chapters. Chapters 1, 2, 5, 6, and 7 deal with emerging areas of cancer therapy, such as the use of interferon, monoclonal antibodies, liposomes, lymphokines, and immunomodulators. The rest of the chapters cover some of the biochemical and enzyme targets in cancer cells, such as polyamines, prostaglandin, thromboxane, leukotrienes, 5a-reductase, aromatase, cell membrane glycoproteins, and sodium flux. The developments in relation to cancer therapy are mentioned in chapters dealing with biochemical approaches. This book is valuable to biologists, biochemists, immunologists, and molecular biologists intending to exploit the unique properties of cancer cells.
Advances in Cancer Research
This comprehensive treatise on the reticuloendothelial system is a project jointly shared by individual members of the Reticuloendothelial (RE) Society and bio medical scientists in general who are interested in the intricate system of cells and molecular moieties derived from these cells which constitute the RES. It may now be more fashionable in some quarters to consider these cells as part of what is called the mononuclear phagocytic system or the lymphoreticular system. Nevertheless, because of historical developments and current interest in the subject by investigators from many diverse areas, it seems advantageous to present in one comprehensive treatise current information and knowled...
The history of the M. D. Anderson Cancer Center vividly reveals how cancer treatment in America -- and our attitudes toward the disease -- has changed since the middle of the twentieth century. One of the preeminent cancer centers in the world, M. D. Anderson is also one of the first medical institutions devoted exclusively to caring for people with cancer and researching treatments and cures for the disease. Historian James S. Olson's narrative relates the story of the center's founding and of the surgeons, radiologists, radiotherapists, nurses, medical oncologists, scientists, administrators, and patients who built M. D. Anderson into the world-class institution it is today. Through interviews with M. D. Anderson's leaders and patients, Olson brings to life the struggle to understand and treat cancer in America. A cancer survivor who has himself been treated at the center, Olson imbues this history with humor, passion, and humanity. -- Helen Valier