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This book is a comprehensive manual to allow both the novice researcher and the expert to set up and carry out quantitative PCR assays from scratch. However, this book also sets out to explain as many features of qPCR as possible, provide alternative viewpoints, methods, and aims to simulate the researchers into generating, interpreting, and publishing data that are reproducible, reliable, and biologically meaningful
This book covers elements of both the data-driven comparative modeling approach to structure prediction and also recent attempts to simulate folding using explicit or simplified models. Despite the unsolved mystery of how a protein folds, advances are being made in predicting the interactions of proteins with other molecules. Also rapidly advancing are the methods for solving the inverse folding problem, the problem of finding a sequence to fit a structure. This book focuses on the various computational methods for prediction, their successes and their limitations, from the perspective of their most well known practitioners.
Based on an extended case-study in the Portuguese call centre sector, this book addresses the themes of the neoliberal economic restructuring of Southern European societies (with an emphasis on the emergence of the categories of precarity and the precariat), the historically and morally embedded nature of value-creation in service production regimes and emerging forms of commodification of the labouring subject in the neoliberal service economy. This book contributes towards: a) a broader moral critique of precarity, focused on scrutinising the links between the historical development of precarious neoliberal service regimes and context-bounded processes of moral dispossession; and, b) expanding current approaches to value extraction and subjectification in call centre work by jointly focusing on the alienable and inalienable properties that make a particular form of labour-power exploitable in an historical, moral and relational embedded reality.
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In this bold book, A. Naomi Paik grapples with the history of U.S. prison camps that have confined people outside the boundaries of legal and civil rights. Removed from the social and political communities that would guarantee fundamental legal protections, these detainees are effectively rightless, stripped of the right even to have rights. Rightless people thus expose an essential paradox: while the United States purports to champion inalienable rights at home and internationally, it has built its global power in part by creating a regime of imprisonment that places certain populations perceived as threats beyond rights. The United States' status as the guardian of rights coincides with, i...
Generational Use of New Media examines and contrasts how younger and older people, representing different generations, engage with the new media that they increasingly encounter in everyday life. Exploring the various assumptions about the degrees to which younger and older people are more or less willing to use, or are capable of using, new media, the social circumstances under which they do so and the very design of those media, this book critically examines the gap that is assumed to exist between younger users of new media and older non-users. Thematically organised and offering comparative analyses of the generational use of new media and technology, this timely volume presents the latest research and rich new empirical material gathered in the EU, USA and Hong Kong, to reflect on societal practices and the practical implications of building a more inclusive information society.