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Paediatric Movement Disorders is an exciting field of Child Neurology. In recent years, an important amount of new knowledge has accumulated at an increasing place, both on basic and on clinical aspects of Child Neurology. Highly qualified experts of the corresponding fields wrote chapters of this book that represent the “state-of-the-art” in this excited field of Chiold Neurology and will prove to be a useful tool to both clinicians and scientists.
This book reflects debates and results which have developed since the introduction of an international system of classifications in epileptology. The creation of such a system was initiated, in the sixties, mainly for practical reasons: growing international exchange had revealed that divergence of terminology in epilepsy had become important enough to prove a serious obstacle to sensible discussions. The Bethel-Cleveland symposia, which was at the origin of this book, aim to bring the excellence of advanced inter-disciplinary and controversial workshops to a larger public. The book concentrates on a selection of topics where progress has been made, where controversies are open or where discussion needs to be stimulated.
This timely reference presents, for the first time, new findings in molecular genetics that are applicable to the epidemiology, pathogenesis, neuropathology, clinical features, and management of ataxia-bridging the gap between scientific and clinical practice. Organized by the distinctive ataxia disorders, their pathogenesis, and management-facilitating quick and efficient diagnoses! Providing complementary sections on the anatomy of the spinocerebellar system, its normal function, and a history of ataxia research and management, the Handbook of Ataxia Disorders clarifies the impact of identifying the molecular causes of ataxia offers in-depth analysis of dominant and recessive and nonheredi...
This work is the result of a recently held International Epilepsy Colloquium on the mesial temporal lobe epilepsies (MTLE) which covered all aspects of this specific group of syndromes (or constellations), from animal model to treatment strategies. Written by international experts from different fields, it aims to provide professionals from neuroscientists to clinical neurologists, neurosurgeons and neuropaedia-tricians dealing with mesial temporal lobe epilepsy, with a concise overview on the current body of knowledge and on emerging concepts and findings.
Recent medical advances have made pregnancy possible for women with heart disease and saved lives. Completely revised and expanded, this latest edition of this successful and authoritative clinical guide provides step-by-step treatment methods in a clear and organized manner. Includes fifteen extensively updated chapters and offers eight new chapters on topics such as cardiopulmonary imaging, prosthetic heart valves, pregnancy after cardiac transplantation, plus the use of diuretics, vasodilators and angiotensin converting enzyme inhibitors in pregnancy.
The multi-authored book intends to describe the neuropathological appearances associated with epilepsy in childhood and in adults and is based on personal experience of authors working at institutions in the UK and USA who have a strong commitment with epilepsy. The literature on the subject is reviewed. Special emphasis is given to correlations between physical signs and symptoms, radiological presentation, suitability to various operative procedures and pathological findings. The book will include chapters by physicians, physiologists, radiologists, neurosurgeons, all with special interest in the field of epilepsy. The description of the pathological features will include immunohistochemical data as well as results of morphometric analysis.
Un DVD inclus avec des séquences vidéos inédites pour chaque chapitre ! L’épileptologie change, et les approches syndromiques sont maintenant complétées par une approche étiologique fondée sur les progrès considérables en génétique. Une approche purement « électro-clinique » n’est plus adaptée aujourd’hui dans bien des cas. Cette 5e édition du « Guide bleu » fait le point sur les plus récents progrès. Ainsi, la structure du livre a un peu évolué, laissant plus de place aux approches : - physiologiques - épidémiologiques - génétiques - thérapeutique Néanmoins, la description des syndromes épileptiques reste au cœur de cet ouvrage. La diversité des contributeurs – coordinateurs et auteurs – confère à ce livre des qualités d’objectivité et de sérieux qui en font la réputation depuis maintenant près de 30 ans.
This volume provides updated information on epilepsy genes, on the clinical picture of genetic epilepsies discovered so far, and on conceptual advances in the complicated area of genotype-phenotype correlations. Recent studies on monogenic epilepsies present new insights into mechanisms whereby a mutation of a single gene, coding for an ion channel, can result in a complex epileptic phenotype. The analysis of genetically-determined epileptogenic dysplasia is advancing our understanding of the role of genes in controlling normal and pathological brain development. The pathogenic mechanisms by which gene mutations determine progressive myoclonus epilepsies offer critical opportunities to understand the role of genetic factors in neurodegenerative phenome-na associated with an even broader range of progressive epilepsy types. The specialists who have contributed to this book are outstanding international experts in their respective fields, ensuring first and foremost that the reviews are of relevance to clinicians dealing with epilepsy in their daily practice, as well as providing the highest quality scientific information for biomedical research.