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Programming is hard. Building a large program is like constructing a steam locomotive through a hole the size of a postage stamp. An artefact that is the fruit of hundreds of person-years is only ever seen by anyone through a lOO-line window. In some ways it is astonishing that such large systems work at all. But parallel programming is much, much harder. There are so many more things to go wrong. Debugging is a nightmare. A bug that shows up on one run may never happen when you are looking for it - but unfailingly returns as soon as your attention moves elsewhere. A large fraction of the program's code can be made up of marshalling and coordination algorithms. The core application can easil...
This series, formerly edited by Heinz Gerischer and Charls V. Tobias, now edited by Richard C. Alkire and Dieter M. Kolb, has been warmly welcomed by scientists world-wide which is reflected in the reviews of the previous volumes: "This is an essential book for researchers in electrochemistry; it covers areas of both fundamental and practical importance, with reviews of high quality. The material is very well presented and the choice of topics reflects a balanced editorial policy that is welcomed." —The Analyst "All the contributions in this volume are well up to the standard of this excellent series and will be of great value to electrochemists.... The editors again deserve to be congratulated on this fine collection of reviews." —Journal of Electroanalytical Chemistry and Interfacial Chemistry "...competently and clearly written." —Berichte der Bunsen- Gesellschaft für Physikalische Chemie
In the cerebellum and basal ganglia, projection neurons are GABAergic; but in the cerebral cortex, there has been a historically strong dichotomy between glutamatergic projection neurons and GABAergic local circuit neurons. While this dichotomy is overwhelmingly the case, it is now clear that a small population of long-distance projecting GABAergic neurons (positive for somatostatin and nNOS, and negative for parvalbumin) occurs in primates, as well as in cats and rodents. Beyond their well-documented existence, however, the functional significance, ontogeny, and connectivity of this intriguing subpopulation remain obscure.