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This book is the first text to provide a comprehensive assessment of the application of fundamental principles of dissolution and drug release testing to poorly soluble compounds and formulations. Such drug products are, vis-à-vis their physical and chemical properties, inherently incompatible with aqueous dissolution. However, dissolution methods are required for product development and selection, as well as for the fulfillment of regulatory obligations with respect to biopharmaceutical assessment and product quality understanding. The percentage of poorly soluble drugs, defined in classes 2 and 4 of the Biopharmaceutics Classification System (BCS), has significantly increased in the moder...
The Fabry-Perot Interferometer: History, Theory, Practice and Applications presents an invaluable introduction to the Fabry-Perot interferometer, including a brief overview of its history, a look at its applications, and plenty of practical advice on how to use the instrument.
This unique reference book is a compendium of makers and manufacturers of every variety of musical instrument made in the United States today. It provides names and addresses of instrument makers indexed alphabetically. Each entry gives all known information on the total and annual number of instruments the maker has produced, the number of workers in the shop, the year the individual or firm began manufacturing instruments, whether the instruments are available on demand or made to order, and whether a brochure is available from the maker. Complete cross-references are provided for companies known by more than one name, for partnerships, and for parent and subsidiary firms. Instruments are ...
Covers receipts and expenditures of appropriations and other funds.
This book is a comprehensive compilation of modern and cutting-edge chromatographic techniques written by pharmaceutical industry experts, academics, and vendors in the field. This book is an inclusive guide to developing all chromatographic methods (such as liquid chromatography and gas chromatography). It covers modern techniques for developing methods using chromatographic development software, requirements for validations, discussion on orthogonality, and how to transfer methods from HPLC to UHPLC. The text introduces some newer techniques that are heavily employed by chemists analyzing proteins and RNAi, as well as novel techniques such as counter current chromatography. This book is valuable for both the novice starting out in undergraduate labs and those who are new to the pharmaceutical industry and is a useful reference for seasoned analysts.
First multi-year cumulation covers six years: 1965-70.