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The Embryo
A variety of new techniques that promise to revolutionize the clinical management of early pregnancy are fully detailed in this state-of-the-art book. Leading international researchers describe fast-moving topics such as embryo manipulation and the diagnosis of congenital abnormalities. The technology of assisted reproduction has made it possible to study living embryonic material for the first time, which has led to rapid advances in our understanding of the human embryo's early development. For example, study of the embryo in the test tube has pointed to early pregnancy loss as a possible cause of later infertility. Even more important, diagnostic tests using sophisticated techniques of mo...
Implantation
The advent of assisted conception procedures such as in-vitro fertili sation (IVF) has provided the impetus for exploration of the factors that lead to the establishment of pregnancy. This collection of papers from leading research workers brings together current concepts of the processes which may be of importance in implantation. The complex signals from the embryo to the ovary, endometrium and myometrium are now being revealed through studies in both primates and other mammalian species. This book addresses the interrelationship of pituitary and ovarian hormones in controlling ovulation and the preparation of the intrauterine environment for implantation. Once fertilisation has occurred a...
HIV, Perinatal Infections, and Therapy
Papers on the role of the placenta in HIV and other perinatal infections. Proceedings from the 12th Rochester Trophoblast Conference, held in Autumn 1992 in Rochester, New York. The first part of the book addresses the role of the placenta in the transmission of the HIV infection, the central focus of the Conference. Other pre-natal infections, including CMV, Vaccina, Parvovirus, Syphillis, and Herpes Simplex, are then considered, and their implications for perinatal health investigated. The importance of cell regulation is alsodiscussed, exploring the controlling factors which modulate the placental cell membrane and metabolic functions, such as genetic imprinting; the regulation of arachidonic acid cascade; autocrine role for human chorionic gonadotropin; biochemical screening for Down's Syndrome; the role of growth factors and interferon; the autoregulation of gas exchange; and the role of uterine cytokines. HENRY THIEDE is Professor of Obstetrics and Gynecology at the University of Rochester. RICHARD K. MILLERteaches in the University of Rochester Medical Center.
Placental Molecules in Hemodynamics, Transport, and Cellular Regulation
Current placental research in Japan, reflecting the adoption of recent biochemical, immunochemical and microbiological knowledge and techniques, and the resulting observation of enzyme activity and transportation of a variety of substances utilising isolated BBM, BBMV, BM and BMV. Also Vol. 10: Early PregnancyCovering: Trophoblast invasion . Angiogenesis and Blood Vessels . Endocrine and Paracine Regulation. With the European Placenta Group
Gametes - The Spermatozoon
This is detailed, comprehensive and timely account of the spermatozoon and its reproductive function.
Gametes - The Oocyte
This volume, and its companion volume on the spermatozoon, provide an authoritative and wide ranging account of the gametes and their reproductive role and function in humans. Acknowledged authorities from around the world contribute a detailed and timely account of the oocyte. The volume starts with an evolutionary perspective before focusing on the molecular and cellular biology of the oocyte and its structure and function. The development and maturation of the oocyte is fully dealt with to include the endocrine and paracrine regulation of ovarian function. Practical issues such as oocyte storage and ovarian stimulation are also fully covered. The causes of female infertility are also an important theme. The volume concludes with a thought provoking chapter on ethical considerations. The volume will be an essential source of information for all clinicians and scientists with an interest in human reproduction.
State-of-the-Art Research on C1q and the Classical Complement Pathway
C1q is the target recognition protein of the classical complement pathway and a major connecting link between innate and acquired immunity. As a charge pattern recognition molecule of innate immunity, C1q can engage a broad range of ligands derived from self, non-self and altered self via its heterotrimeric globular (gC1q) domain and thus trigger the classical complement pathway. The trimeric gC1q signature domain has been identified in a variety of non-complement proteins that can be grouped together as a C1q family. C1q circulates in serum as part of the C1 complex, in association with a catalytic tetrameric assembly of two homologous yet distinct serine proteases, C1r and C1s. Binding of ...
The Uterus
The series provides an essential source of information for all trainees in obstetrics, gynaecology, andrology and reproductive medicine, and will also be of interest to reproductive biologists and geneticists, physiologists and endocrinologists.
Implantation and Early Pregnancy in Humans
Over the last two decades, major advances in ovulation induction and assisted reproductive technologies have been made, and now, in the 1990s, the aim is to concentrate talent and efforts on the next obvious step - achieving a high rate of successful full-term pregnancies by concentrating on implantation and early pregnancy. Investigating and surmounting the disorders associated with this critical period are the major hurdles, which, through research and clinical efforts, must be overcome in order to achieve this goal.
