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Lead is a ubiquitous metal in the environment, and its adverse effects on human health are well documented. Lead interacts at multiple cellular sites and can alter protein function in part through binding to amino acid sulfhydryl and carboxyl groups on a wide variety of structural and functional proteins. In addition, lead mimics calcium and other divalent cations, and it induces the increased production of cytotoxic reactive oxygen species. Adverse effects associated with lead exposure can be observed in multiple body systems, including the nervous, cardiovascular, renal, hematologic, immunologic, and reproductive systems. Lead exposure is also known to induce adverse developmental effects ...
Clinical & Experimental Toxicology of Organophosphates and Carbamates considers the histochemical localization of cholinesterase in anticholinesterase poisoning. This book is organized into eight parts encompassing 59 chapters that discuss the pharmacology and toxicology of carbamates, as well as the neurobehavioral toxicology of anticholinesterases. Some of the topics covered in the book are the overview of biological and clinical aspects of organophosphates and carbamates; biochemical determination of cholinesterase activity in fluids and tissues; intermediate syndrome in anticholinesterase neurotoxicity; structure-activity relationships and anticholinesterase activity; and the molecular e...
Brain disordersâ€"neurological, psychiatric, and developmentalâ€"now affect at least 250 million people in the developing world, and this number is expected to rise as life expectancy increases. Yet public and private health systems in developing countries have paid relatively little attention to brain disorders. The negative attitudes, prejudice, and stigma that often surround many of these disorders have contributed to this neglect. Lacking proper diagnosis and treatment, millions of individual lives are lost to disability and death. Such conditions exact both personal and economic costs on families, communities, and nations. The report describes the causes and risk factors associated with brain disorders. It focuses on six representative brain disorders that are prevalent in developing countries: developmental disabilities, epilepsy, schizophrenia, bipolar disorder, depression, and stroke. The report makes detailed recommendations of ways to reduce the toll exacted by these six disorders. In broader strokes, the report also proposes six major strategies toward reducing the overall burden of brain disorders in the developing world.
Integrating health objectives and international trade policies.
A map of the relationship between work and health that is truly global--both geographically and in its coverage of the impact of work on the health of individuals, families, and societies, has not previously been drawn. Global Inequalities at Work is the first book to fill in the map. Drawing from studies done around the world, it critically examines the many ways in which work is affecting health around the world. The first section covers the wide range of risks--physical, chemical, and social--tot he health of employees in agricultural, industrial, and post-industrial workplaces. Part II provides a detailed analysis of how working conditions can dramatically influence the health and welfar...
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Studies in Environmental Science encompasses a broad range of topics within the field of environmental science and technology. Volume 18 covers the Proceedings of the Sixth International Workshop of the Scientific Committee on Pesticides of the International Association on Occupational Health, Buenos Aires and San Carlos de Bariloche.
This book, written from a patient's perspective, first defines chemical sensitivity, then describes its effects, and discusses strategies for dealing with it. A complete resource listing, information on documenting a case, expert opinions on CS and an examination of the issues are included. An appendix provides detoxification data.
The International Water Management Institute (IWMI) has, for many years, been involved in research on pesticide poisoning to analyse the reasons for the high number of pesticide poisoning cases in Sri Lanka and discuss ways of controlling the problem through changes in agricultural practices and community involvement. More recently, research has focused on risk factors for deliberate and occupational pesticide poisoning and on the impact that a shift towards Integrated Pest Management (IPM) will have on the health of farming families. A workshop on Pesticides: Health Impacts and Alternative was held at the Colombo Hilton Hotel on 24 January 2002. The workshop marked the end of IWMI’s research on pesticide poisoning in Sri Lanka and provided researchers and policy makers from various. A disciplines such as health, environment, and agriculture an opportunity to share and discuss recent findings and to discuss strategies to reduce pesticide poisoning. This paper presents the workshop proceedings and includes a resource handbook for Sri Lanka on health impacts of pesticides and alternatives by listing names of relevant institutes, addresses and annotated references.
Field Worker Exposure During Pesticide Application