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This book focuses on the neuropsychopharmacology of serotonin and its role in sleep and wakefulness, presenting neurochemical, electrophysiological, and neuropharmacological approaches to understand the mechanisms of serotonin and related substances. Covering core and contemporary topics in the area, this volume is valuable for all researchers interested in interdisciplinary studies concerning drugs affecting the central nervous system.
Serotonin (5-hydroxytryptamine, often cited as 5-HT) is one of the major excitatory neurotransmitter, and the serotonergic system is one of the best studied and understood transmitter systems. It is crucially involved in the organization of virtually all behaviours and in the regulation of emotion and mood. Alterations in the serotonergic system, induced by e.g. learning or pathological processes, underlie behavioural plasticity and changes in mood, which can finally results in abnormal behaviour and psychiatric conditions. Not surprisingly, the serotonergic system and its functional components appear to be targets for a multitude of pharmacological treatments - examples of very successful d...
With contributions by numerous experts
This book asks an important question: If you were born in rural England in 1837 and died in 1901 and never travelled more than thirty miles in any direction would you have seen a hippopotamus before you died? The answer is, surprisingly, yes. In fact, the roads of England were thronged with all manner of creatures. There were even exotic butterfly farms. Kangaroos hopped around the lawns of stately homes, tigers prowled the backstreets of the East End, a tapir terrorised the people of Rochdale, an angry cassowary pursued a Lord as he was out for his daily ride, a boa constrictor got loose in Tunbridge Wells. This book is the first to explore the full and surprising extent of the exotic anima...
This magnificently illustrated people’s history celebrates the extraordinary feats of cultivation by the working class in Britain, even if the land they toiled, planted, and loved was not their own. Spanning more than four centuries, from the earliest records of the laboring classes in the country to today, Margaret Willes's research unearths lush gardens nurtured outside rough workers’ cottages and horticultural miracles performed in blackened yards, and reveals the ingenious, sometimes devious, methods employed by determined, obsessive, and eccentric workers to make their drab surroundings bloom. She also explores the stories of the great philanthropic industrialists who provided gardens for their workforces, the fashionable rich stealing the gardening ideas of the poor, alehouse syndicates and fierce rivalries between vegetable growers, flower-fanciers cultivating exotic blooms on their city windowsills, and the rich lore handed down from gardener to gardener through generations. This is a sumptuous record of the myriad ways in which the popular cultivation of plants, vegetables, and flowers has played—and continues to play—an integral role in everyday British life.
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