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The problem of electron transfer phosphorylation was first formu lated in 1939 by Belitser and Tsibakova I who introduced the "P: 0" criterion and showed that this ratio is more than 1. The authors noted that such a high value of the phosphorylation coefficient suggests a fundamental difference in the mechanisms of A TP formation coupled with respiration, and glycolysis, since in the latter case, the amount of the ATP synthesized is equal to that of the substrate utilized. A lot of hypothetical schemes were put forward to explain the nature of coupling between electron transfer and phosphorylation, but none of them solved the problem. Only quite recently, one hypo thetical scheme of energy coupling, viz. Mitchell's chemiosmotic concept, 2.3 was supported by experimental data which allow us to prefer it to alternative possibilities. In this paper, I shall try to substantiate the statement that oxidation and phosphorylation can be coupled via a membrane potential as was postulated by Mitchell.
Proceedings of the NATO Advanced Study Institute on Plasma Treatments and Deposition of Polymers, Acquafredda di Maratea, Italy, May 19-June 2, 1996
Progress in Phytochemistry, Volume 7, provides an overview of the state of knowledge in phytochemical research. This book is dedicated to Dr. E. C. Bate-Smith, CBE, one of the leading pioneers of the subject. Many of the topics in this volume represent aspects of phytochemical research which he has encouraged in others or to which he has himself contributed. The book begins with a chapter on chemotaxonomy. It considers in critical detail the contribution of isozyme electrophoresis to the understanding of plant variation at the population level. This is followed by separate chapters on carbonic anhydrase; biochemical developments in seed germination; the role of plant hormones in the control of the germination process; non-protein amino acids of plants; and the production of phenolics in plants in response to microbial disease. Subsequent chapters cover the terpenoid variation encountered within a single genus of marine algae, among species of Laurencia; and plants with hallucinogenic activity.
Addictions is designed for students and professionals who wish to gain an authoritative, research-based knowledge of a variety of addictions. It covers issues such as diagnosis, epidemiology, psychological and biological models and treatments and draws on the research of The National Drug and Alcohol Research Centre, Sydney, and on a variety of international surveys. Addictions is written by experts in the field of drug and alcohol research, and takes into account a variety of theories, including neuroscientific, psychological, behavioural, personality and rational choice. It includes material on: The nature of addiction and who becomes addicted The health consequences of alcohol and other drug dependence Theories and causes of addiction It provides a timely and accessible introduction to this field.
Vols. for 1963- include as pt. 2 of the Jan. issue: Medical subject headings.