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Integrating both theoretical and applied aspects of electrochemistry, this acclaimed monograph series presents a review of the latest advances in the field. The current volume includes chapters on the mechanism of nerve excitation from an electrochemical standpoint, the electronic factor in the kinetics of charge-transfer reaction, and five other subjects.
Quality of life (QoL) is a broad concept that has many definitions and meanings depending on the context under consideration. It can be perceived as the overall enjoyment of life, and a multidimensional concept which emphasizes the self-perceptions of an individual’s current state of mind, which is affected in a complex way by the person’s physical health, psychological state, personal beliefs, social relationships, and their relationship to salient features of their environment. On the other hand, demographic data suggests an increased need for workers worldwide and a rapid aging trend in the active workforce as well as in general. This trend of workforce deficit and population aging will be even more prominent in the future. Therefore, in order to have and sustain a healthy, motivated, and productive workforce, but also healthy, independent, and active elderly adults, one must improve their QoL, and vice versa. Improving QoL will improve general public health, and in turn create communities who can contribute in diverse and positive ways to both promote and sustain health for future generations.
This book provides the most updated information of how membrane lipids mediate protein signaling from studies carried out in animal and plant cells. Also, there are some chapters that go beyond and expand these studies of protein-lipid interactions at the structural level. The book begins with a literature review from investigations associated to sphingolipids, followed by studies that describe the role of phosphoinositides in signaling and closing with the function of other key lipids in signaling at the plasma membrane and intracellular organelles.
Ubiquitination and Sumoylation are two important posttranslational modifications that play pivotal roles in a variety of biological functions. Although Ubiquitination is traditionally viewed as a critical mark targeting proteins for proteasome-dependent degradation, recent studies reveal that it also plays nonproteolytic functions. In contrast, Sumoylation is long thought not to target proteins for degradation, accumulating evidence suggests that it can serve a priming effect prerequisite for ubiquitination, thereby inducing protein ubiquitination and degradation. Thus, there is an important cross-talk between sumoylation and ubiquitination in determining protein fate. Deregulation in these two marks may cause aberrant activity of proteins and in turn contributes to cancer development. In this Research Topic, we accept review articles, perspectives, research articles covering any one or both of these two posttranslational modifications in regulating diverse signal transduction pathways and providing the novel insights in unraveling the puzzle as to how they may regulate cancer progression and metastasis.
Allergic rhinitis, while troublesome for a patient, may be also a challenge for the physician. That is why physicians must still learn more on the pathophysiology, clinical spectrum and novel diagnostic and therapeutic approaches to the disease. The chapters of this volume address a variety of important topics related to allergic rhinitis. They begin with a description of innovative translational approaches allowing for unification of animal and human models. Contributing authors provide up-to-date reviews of clinical aspects of allergic rhinitis in children, its association with bronchial asthma and other co-morbid conditions. They also discuss the impact of allergic rhinitis on sleep and sports. Together with articles on diagnostic approaches as well as novel treatments, the book offers a comprehensive and stimulating review of the topic. May this book find a wide readership among allergists and other physicians interested in allergic disease, and also among pediatricians, general practitioners and other specialists who increasingly have to deal with this seemingly benign, but sometimes extremely troublesome, disease.
Technology now affects almost every aspect of Water Supply Management, Operation, Planning and Design; the speed of development means that assessing what is "new" is sometimes difficult. Old ideas can now be applied because of new technology; technology is now revealing problems that were unnoticed 10 years ago. Some emerging technologies promise much but are still underdeveloped for use in real world conditions, while we should always remember that "new" technology depends upon the state of development in respective countries, a point which is particularly relevant to the NATO Advanced Study Institute, for which this book has been produced. Thus our objective in producing the book has been ...
Proceedings of the Second "Rencontres de l'observatoire", Observatoire de Paris, Meudon, France
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This edited book brings together a diverse group of environmental science, sustainability, and health researchers to address the challenges posed by global mass poisoning caused by chromium contamination of soil and plants. In recent years, contamination of the environment by chromium has become a major concern. Chromium is a non-degradable, harmful, and toxic pollutant which negatively affects the environment. It is unique among the heavy metals found in industrial wastewater and sewage and sludge, as it may exist as a trivalent cation and as anion in the hexavalent state in the pH range of agricultural soils. It is used on a large scale in many different industries, including metallurgy, e...
The influence of the gut microbiome on human health and disease has been established in recent years through advances in high-throughput DNA sequencing. The Gut Microbiome: Bench to Table presents a scientific introduction to this topic, analyzes research on how the microbiome is affected by nutrients, and how dietary modifications can alter the microbiome. The Gut Microbiome: Bench to Table is divided into three sections. The first section details the current state of laboratory-scale analysis of gut microbiome samples and how we can identify the communities and their functional repertoire. Section II explains the next phase of translational research models such as preclinical, animal studi...