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This volume, the sixth in the IBAGS series, summarizes major contributions in clinical and basic research on the basal ganglia. The sixth meeting of the Society was held on Cape Cod, in the state of Massachusetts, USA, in October, 1998. Altogether 16 countries were represented by 227 participants. This volume contains papers contributed by participants. The focus of the sixth triennial IBAGS meeting, and of this volume, was to bring to gether leaders in basic and clinical science to address two sets of still-persisting questions in the field. The first set focuses on the functions of the basal ganglia in health and disease: What are the core functions of the basal ganglia and cortico-basal g...
A collection of up-to-date methods and data available in neuroscience, addressing issues from the molecular to the cellular and systems level of analysis. This volume includes coverage of electrophysical recording, neuronal cell culture, and preparation of tissues for microscopy or analysis.
This third edition of the standard reference on the nervous system of the rat is a complete and updated revision of the 1994 second edition. All chapters have been extensively updated, and new chapters added covering early segmentation, growth factors, and glia. The book is now aligned with the data available in the Rat Brain in Stereotaxic Coordinates, making it an excellent companion to this bestselling atlas. Physiological data, functional concepts, and correlates to human anatomy and function round out the new edition. - Designed to be used in conjunction with the bestselling Rat Brain in Stereotaxic Coordinates - New to this edition is inclusion of physiological data, functional concepts, and correlates to human anatomy and function in each chapter - Contains new chapters on early segmentation of the central nervous system, growth factors and glia
Over the past 25 years the amount of data pertaining to the GABAergic function in the basal ganglia has increased dramatically. GABA and the Basal Ganglia - From Molecules to Systems is a comprehensive review of the current state-of-the-art of knowledge about the neuroanatomy, neuropharmacology and neurophysiology of the basal ganglia, focusing on its GABAergic microcircuitry. It serves as a complete reference to the body of knowledge about the basal ganglia, its constituent neurons, and their interconnections. This volume is designed to serve as a convenient all-in-one review and reference for experienced basal ganglia researchers as well as an introduction to the functional organization of the basal ganglia and its GABAergic circuitry for students and researchers new to the field.* Reviews the anatomy, physiology and pharmacology of the basal ganglia itself in addition to focusing on the GABAergic circuitry of the basal ganglia* Authors of each chapter leading internationally acclaimed experts in basal ganglia research
This volume, The Basal Ganglia VII, is derived from the proceedings ofthe Seventh Triennial Meeting of the International Basal Ganglia Society (IBAGS). The Meeting was held from II - 15 February 2001 at The Copthorne Resort, Waitangi, Bay of Islands, New Zealand, the site of the signing of the Treaty ofWaitangi in 1840 and the traditional birth-place of the New Zealand Nation. As at previous Meetings, our aim was to hear and discuss new ideas and research developments on the basal ganglia and the implications of these findings for novel treatment strategies for basal ganglia disorders. The International Basal Ganglia Society (IBAGS) was founded in September 1983 when a small group of about 50 neuroscientists and clinicians with a passion for research on the basal ganglia met for a three day meeting in a small isolated seaside resort, Lome, 150km from Melbourne in Australia. The meeting was organised by John McKenzie and was so successful that the participants decided to establish IBAGS and to meet every 3 years at an isolated seaside resort in different countries of the world.
Microcircuits are the specific arrangements of cells and their connections that carry out the operations unique to each brain region. This resource summarizes succinctly these circuits in over 40 regions - enabling comparisons of principles across both vertebrates and invertebrates. It provides a new foundation for understanding brain function that will be of interest to all neuroscientists. Oxford Clinical Neuroscience is a comprehensive, cross-searchable collection of resources offering quick and easy access to eleven of Oxford University Press's prestigious neuroscience texts. Joining Oxford Medicine Online these resources offer students, specialists and clinical researchers the best quality content in an easy-to-access format.
''Emphasis on new issues and emerging concepts insures that the information presented is still timely...A compelling source of information on recent research in the field.'' ---Journal of Chemical Neuroanatomy, May 1997
This book addresses a fundamental question about the nature of behavior: how does the brain process reward and makes decisions when facing multiple options? The book presents the most recent and compelling lesion, neuroimaging, electrophysiological and computational studies, in combination with hormonal and genetic studies, which have led to a clearer understanding of neural mechanisms behind reward and decision making. The neural bases of reward and decision making processes are of great interest to scientists because of the fundamental role of reward in a number of behavioral processes (such as motivation, learning and cognition) and because of their theoretical and clinical implications f...
The Novartis Foundation Series is a popular collection of the proceedings from Novartis Foundation Symposia, in which groups of leading scientists from a range of topics across biology, chemistry and medicine assembled to present papers and discuss results. The Novartis Foundation, originally known as the Ciba Foundation, is well known to scientists and clinicians around the world.
This book provides a unique and timely multidisciplinary synthesis of our current knowledge of the anatomy, pharmacology, physiology and pathology of the substantia nigra pars compacta (SNc) dopaminergic neurons. The single chapters, written by top scientists in their fields, explore the life cycle of dopaminergic neurons from their birth to death, the cause of Parkinson's disease, the second most common and disabling condition in the elderly population. Nevertheless, the intracellular cascade of events leading to dopamine cell death is still unknown and, consequently, treatment is symptomatic rather than preventive. The mechanisms by which alterations cause neuronal death, new therapeutic approaches and the latest evidence of a possible de novo neurogenesis in the SNc are reviewed and singled out in different chapters. This book bridges basic science and clinical practice and will prepare the reader for the next few years, which will surely be eventful in terms of the progress of dopamine research.