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An essential update and comprehensive review Patients undergoing solid organ and hematopoietic stem cell transplantation frequently develop skin diseases that can be challenging to themselves and their doctors. In the first part of this volume, prevalent epidemiological, clinical and histological skin problems of solid organ recipients are discussed. Pre- and posttransplant management as well as follow-up programs are presented focusing on European and Swiss guidelines. A special chapter is dedicated to immunosuppressive drugs considering current standards, and new and upcoming medication. The second part starts with a summary of historical aspects of hematopoietic stem cell transplantation,...
Introduces new material that reflects the significant advances and developments in the field of clinical laboratory immunology. • Provides a comprehensive and practical approach to the procedures underlying clinical immunology testing. • Emphasizes molecular techniques used in the field of laboratory immunology. • Updates existing chapters and adds significant new material detailing molecular techniques used in the field. • Presents guidelines for selecting the best procedures for specific situations and discusses alternative procedures. • Covers aspects of immunology related disciplines such as allergy, autoimmune diseases, cancers, and transplantation immunology.
This book provides up-to-date information on immunogenetics of fungal diseases in the context of primary and acquired immunodeficiencies. Different aspects of this emerging field are covered, including epidemiology of fungal diseases, innate and adaptive antifungal immunity, and the role of immunogenetics in defining susceptibility to fungal diseases in primary (CMC, CGD, etc.) immunodeficiencies and hematologic patients. The available information will also be discussed in the scope of new biomarker discovery and development of immunotherapeutic approaches for personalized diagnostics and therapy. The book addresses Professors, researchers and advanced students of Medicine, Immunology, Microbiology and Genetics.
Autoimmune disorders are caused due to break down of the immune system, which consequently fails in its ability to differentiate "self" from "non-self" in the context of immunology. The diseases are intriguing, both clinically and immunologically, for their diversified clinical phenotypes and complex underlying immunological mechanisms. This book offers cutting-edge information on some of the specific autoimmune disease phenotypes, respective diagnostic and prognostic measures, classical and new therapeutic options currently available, pathogenesis and underlying mechanisms potentially involved, and beyond. In the form of Open Access, such information is made freely available to clinicians, basic scientists and many others who will be interested regarding current advances in the areas. Its potential readers will find many of the chapters containing in-depth analysis, interesting discussions and various thought-provoking novel ideas.
A comprehensive and updated volume for the clinical virologist. • Details laboratory procedures for detecting and handling viruses, from specimen requirements and quality assurance to virus detection and identification, from the fundamentals through the latest molecular methods. • Presents the most current knowledge on the wide range of specific viral pathogens. • Includes information on services provided by federal and state public health virology laboratories. • Provides essential information for clinicians and laboratory virologists.
2004 marks the 100th anniversary of the first description of the autoimmune disease paroxysmal cold hemoglobinuria, a rare hemolytic disorder, by Julius Donath and Karl Landsteiner. After a century of research, the list of autoimmune diseases has become impressive. With a prevalence of approximately 5% of the world-wide population, these chronic, debilitating conditions affect almost every major organ of the body and, for reasons that remain unclear, are much more prevalent in woman than in men. Despite our rapidly expanding knowledge of the cellular and molecular pathways that govern a normal immune response, deciphering the precise etiology of autoimmune diseases remains an important chall...
This book is a centennial volume celebrating the enormous progress made in hematology in the 20th century. It is edited by Marshall Lichtman, a distinguished senior hematologist, past president of the American Society of Hematology, and co-editor of the leading text in the field. Hematology is a compendium, with commentaries, of the most important papers published in the field from 1900-1999. The book will be useful for reference--many of the older papers can no longer be found in most libraries, yet are still referred to in current publications, especially review articles--as well as teaching. The Editor and a team of associate editors have included the most important papers covering eight ...
This comprehensive, full color hematopathology reference book emphasizes immunophenotpic features, cytogenetic studies, and diagnostic molecular aspects. Hematopathology begins with introductions to morphologic evaluation of the hematopoietic tissues and principles of immunophenotyping, cytogenetics and molecular studies followed by chapters dedicated to different types of hematologic disorders. Each chapter starts with a basic overview of hematopathlogy followed by a comprehensive review of immunophenotypic, cytogenetic and molecular findings. The text is balanced with large numbers of full color images, graphs, charts, and tables to assist the reader in understanding these highly technical issues. - Emphasizes the immunophenotypic features, cytogenetic studies, and diagnostic molecular aspects of hematology - Features hundreds of images, charts and tables for the identification of hematologic disorders not only based on histopathologic features, but also with the use of advanced accessory techniques
The present book is aimed to provide the readers with current trends in the field of Mycology in general and fungal biotechnology in particular. The book would be of utmost importance to students, researchers and teachers of botany, mycology, microbiology, fungal biotechnology and nanotechnology. The readers should find the book full of information and reader-friendly.
Our goal for this book is to examine the contemporary therapy of rheumatoid arthritis (RA) from the increasingly important perspective of impact upon quality of life, costs and long-term health outcomes. For too long the focus has been on short term, symptomatic, and surrogate indicator outcomes. Yet RA is a life-long disor der with the majority of impact on an individual patient many years following onset. Further, even in the short-term, researchers and rheumatologists have tended to emphasize measurements of disease activity such as joint counts, ESR and physi cian's opinion as to the amount of disease activity present. It is only relatively recently that measures of structural damage, qu...