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Mitochondrial Biogenesis and Genetics
The critically acclaimed laboratory standard for forty years, Methods in Enzymology is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerlyawaited, frequently consulted, and praised by researchers and reviewers alike. More than 250 volumes have been published (all of them still in print) and much of the material is relevant even today--truly an essential publication for researchers in all fields of life sciences. Key Features * Structural and functional analysis of oxidative phosphorylation complexes * Import of proteins and RNA into mitochondria * Ion and metabolite transport systems in mitochondria * Biophysical methods for mitochondrial function analysis * Mitochondrial inheritance and turnover.
Crusaders of the Jungle
A challenge came to the Spanish Kings with the discovery of the New World...a challenge to the conquest of empire for Spain, of souls for “the Holy Mother Roman Catholic Church.” And like the conquistadores, the Spanish padres received the challenge eagerly. Armed with breviary and crucifix, inspired by an undying faith, they went forth to conquer the legions of Satan beyond the Ocean Sea. In South America the padres found no El Dorado, no fabled cities of gold, but only tribes of naked savages dwelling in a “Green Hell.”...The Guarani Indians of Paraguay named their children in a repulsive ceremony at which both parents and children partook of a soup made from the flesh of a prisone...
Oxford Studies in Ancient Philosophy
Oxford Studies in Ancient Philosophy is a volume of original articles on all aspects of ancient philosophy. The articles may be of substantial length, and include critical notices of major books. OSAP is now published twice yearly, in both hardback and paperback. "'Have you seen the latest OSAP?' is what scholars of ancient philosophy say to each other when they meet in corridors or on coffee breaks. Whether you work on Plato or Aristotle, on Presocratics or sophists, on Stoics, Epicureans, or Sceptics, on Roman philosophers or Greek Neoplatonists, you are liable to find OSAP articles now dominant in the bibliography of much serious published work in your particular subject: not safe to miss...
New Therapies for Neonatal Respiratory Failure
The diagnosis and treatment of respiratory problems in the newborn have advanced significantly over recent years, although respiratory failure remains an important cause of neonatal mortality and morbidity. This book provides a comprehensive overview of respiratory physiology in the newborn, and of the mechanism underlying respiratory failure in this age group. It goes on to present in detail the techniques, both novel and well established, for effective ventilatory support. In presenting and evaluating the available treatment modalities, the authors consider not only clinical indications, modes of delivery and monitoring, but also complications and outcomes. Comprehensive and up to date, this is an essential handbook and reference for clinicians in neonatal medicine, that will help to optimise their management of respiratory failure in the newborn.
Peroxiporins
To produce energy, aerobic organisms transform oxygen molecules into water. This reductive mechanism yields toxic radical intermediates, collectively known as reactive oxygen species (ROS). Paradoxically, these physiological processes entail the production of potentially damaging species. Evolution has turned this apparent disadvantage into an opportunity for transmitting information. As a result, redox signaling within the cell is an efficient exquisitely organized process. A key element for its regulation is the physical separation of sources and targets into different cell compartments. Peroxiporins, H2O2 transporting proteins spanning biological membranes, distribute the signal from emit...
