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The development of the cardiovascular system is a rapidly advancing area in biomedical research, now coupled with the burgeoning field of cardiac regenerative medicine. A lucid understanding of these fields is paramount to reducing human cardiovascular diseases of both fetal and adult origin. Significant progress can now be made through a comprehensive investigation of embryonic development and its genetic control circuitry. Heart Development and Regeneration, written by experts in the field, provides essential information on topics ranging from the evolution and lineage origins of the developing cardiovascular system to cardiac regenerative medicine. A reference for clinicians, medical rese...
An explosive increase in the knowledge of the effects of chemical and physical agents on biological systems has led to an increased understanding of normal cellular functions and the consequences of their perturbations. The 14-volume Second Edition of Comprehensive Toxicology has been revised and updated to reflect new advances in toxicology research, including content by some of the leading researchers in the field. It remains the premier resource for toxicologists in academia, medicine, and corporations. Comprehensive Toxicology Second Edition provides a unique organ-systems structure that allows the user to explore the toxic effects of various substances on each human system, aiding in providing diagnoses and proving essential in situations where the toxic substance is unknown but its effects on a system are obvious. Comprehensive Toxicology Second Edition is the most complete and valuable toxicology work available to researchers today. Contents updated and revised to reflect developments in toxicology research Organized with a unique organ-system approach Features full color throughout Available electronically on sciencedirect.com, as well as in a limited-edition print version
The mendicant Orders had a profound impact on urban society, life and culture from the thirteenth century onwards. Being engaged in extensive and ambitious pastoral activities they depended on outside support for their material existence. Their influence extended into ecclesiastical as well as secular affairs, leading to the creation of a network of connections to different social groups and on occasion even an involvement in politics. The role of the mendicants in a medieval capital has not yet been systematically studied. A first attempt to study a city of this scale is here made for London.
This multi-volume set within International Review of Cytology encompasses the recent advances in the understanding of structure-function relationships at the molecular level of receptors, transporters, and membrane proteins. Several diverse families of membrane receptors/proteins are discussed with respect to the molecular and cellular biology of their synthesis, assembly, turnover, and function. Included are such receptor superfamilies as G-proteins, immunoglobulins, ligand-gated receptors, interleukins, and tyrosine kinases as well as such transporter/protein families as pumps, ion channels, and bacterial transporters. Each section of each volume features a "perspectives/commentary" chapter which includes comments on the recent advances and predictions on new directions. Written by acknowledged experts in the field, this volume, 137C, highlights recent developments in pumps, channels, and transporters. - The latest on several important protein families, including: - The G-protein-coupled receptors - The interleukin receptors - Sugar transporters - Several ion channels and pumps
Written by contributors representing the Anglican, Roman Catholic, Free Church, and Orthodox traditions, this collection examines the nature and form of individual Christian devotion throughout the centuries.
One of the enduring ironies of medieval history is the fact that a group of Italian lay penitents, begging in sackcloths, led by a man who called himself simple and ignorant, turned in a short time into a very popular and respectable order, featuring cardinals and university professors among its ranks. Within a century of its foundation, the Order of Friars Minor could claim hundreds of permanent houses, schools, and libraries across Europe; indeed, alongside the Dominicans, they attracted the best minds and produced many outstanding scholars who were at the forefront of Western philosophical and religious thought. In The Poor and the Perfect, Neslihan Şenocak provides a grand narrative of ...
Extractive Metallurgy of Rare Earths compiles information from scattered sources that is often available only to specialists. It provides a complete and usable survey of the rare earth resources, extraction, and production of numerous end products that translates to both laboratory and industrial settings. This book is a source of industry expertis
A History of Preaching brings together narrative history and primary sources to provide the most comprehensive guide available to the story of the church's ministry of proclamation. Bringing together an impressive array of familiar and lesser-known figures, Edwards paints a detailed, compelling picture of what it has meant to preach the gospel. Pastors, scholars, and students of homiletics will find here many opportunities to enrich their understanding and practice of preaching. Volume 1 contains Edwards's magisterial retelling of the story of Christian preaching's development from its Hellenistic and Jewish roots in the New Testament, through the late-twentieth century's discontent with out...
The ultimate clinical implementation of embryonic stem cells will require methods and protocols to turn these unspecialized cells into the fully functioning cell types found in a wide variety of tissues and organs. In order to achieve this, it is necessary to clearly understand the signals and cues that direct embryonic stem cell differentiation. This book provides a snapshot of current research on the differentiation of embryonic stem cells to a wide variety of cell types, including neural, cardiac, endothelial, osteogenic, and hepatic cells. In addition, induced pluripotent stem cells and other pluripotent stem cell sources are described. The book will serve as a valuable resource for engineers, scientists, and clinicians as well as students in a wide range of disciplines.