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Drug Discovery
Sets forth the history, state of the science, and future directions of drug discovery Edited by Jie Jack Li and Nobel laureate E. J. Corey, two leading pioneers in drug discovery and medicinal chemistry, this book synthesizes great moments in history, the current state of the science, and future directions of drug discovery into one expertly written and organized work. Exploring all major therapeutic areas, the book introduces readers to all facets and phases of drug discovery, including target selection, biological testing, drug metabolism, and computer-assisted drug design. Drug Discovery features chapters written by an international team of pharmaceutical and medicinal chemists. Contribut...
Understanding the Enrichment of Heavy Elements by the Chemodynamical Evolution Models of Dwarf Galaxies
This book addresses the mechanism of enrichment of heavy elements in galaxies, a long standing problem in astronomy. It mainly focuses on explaining the origin of heavy elements by performing state-of-the-art, high-resolution hydrodynamic simulations of dwarf galaxies. In this book, the author successfully develops a model of galactic chemodynamical evolution by means of which the neutron star mergers can be used to explain the observed abundance pattern of the heavy elements synthesized by the rapid neutron capture process, such as europium, gold, and uranium in the Local Group dwarf galaxies. The book argues that heavy elements are significant indicators of the evolutionary history of the early galaxies, and presents theoretical findings that open new avenues to understanding the formation and evolution of galaxies based on the abundance of heavy elements in metal-poor stars.
Annual Statistical Report
1867/68- include the Statistical report of the Secretary of State in continuation of the Annual report of the Commissioners of Statistics.
