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Evolutionary Biology of Aging
This unique book looks at the biology of aging from a fundamentally new perspective, one based on evolutionary theory rather than traditional concepts which emphasize molecular and cellular processes. The basis for this approach lies in the fact that natural selection, as a powerful determining force, tends to decline in importance with age. Many of the characteristics we associate with aging, the author argues, are more the result of this decline than any mechanical imperative contained within organic structures. This theory in turn yields the most fruitful avenues for seeking answers to the problem of aging, and should be recognized as the intellectual core of gerontology and the foundation for future research. The author ably surveys the vast literature on aging, presenting mathematical, experimental, and comparative findings to illustrate and support the central thesis. The result is the first complete synthesis of this vital field. Evolutionary biologists, gerontologists, and all those concerned with the science of aging will find it a stimulating, strongly argued account.
Transplant
Drawing on firsthand experience, a pioneer in organ transplantation discussesthe amazing advances in the field. 53 illustrations.
Hitler's Gift
Between 1901 and 1932, Germany won a third of all the Nobel Prizes for science. With Hitler's rise to power and the introduction of racial laws, starting with the exclusion of all Jews from state institutions, Jewish professors were forced to leave their jobs, which closed the door on Germany’s fifty-year record of world supremacy in science. Of these more than 1,500 refugees, fifteen went on to win Nobel Prizes, several co-discovered penicillin—and more of them became the driving force behind the atomic bomb project. In this revelatory book, Jean Medawar and David Pyke tell countless gripping individual stories of emigration, rescue, and escape, including those of Albert Einstein, Fritz...
The PKU Paradox
Named one of the "Ten must-read science histories" by Science Magazine In a lifetime of practice, most physicians will never encounter a single case of PKU. Yet every physician in the industrialized world learns about the disease in medical school and, since the early 1960s, the newborn heel stick test for PKU has been mandatory in many countries. Diane B. Paul and Jeffrey P. Brosco’s beautifully written book explains this paradox. PKU (phenylketonuria) is a genetic disorder that causes severe cognitive impairment if it is not detected and treated with a strict and difficult diet. Programs to detect PKU and start treatment early are deservedly considered a public health success story. Some...
Perspectives on the Coordination of Movement
Is there a `right way' to study coordination? What experimental paradigms are appropriate? Are there laws and principles that the biological system uses to coordinate movement? Do all biological systems - human and otherwise - share these same principles? Is coordination inherited or acquired? Is it a central nervous system, muscular, or mechanical problem? Indeed, what is coordination and how can it be quantified?This volume attempts to help to answer some of these questions by bringing together a collection of conceptual approaches to and empirical investigations of the coordination of movement. The authors of the chapters are well known and respected researchers from a variety of discipli...
Epigenetics
“If you want to understand evolution, you need to understand the murky world of epigenetics. A hearty congratulations should be paid to Hallgrimsson and Hall, who provide reliable and steady illumination.”-Bernard Wood, Center for the Advanced Study of Hominid Paleobiology, George Washington University
The Spiritual Quest
Robert Torrance's wide-ranging, innovative study argues that the spiritual quest is rooted in our biological, psychological, linguistic, and social nature. The quest is not, as most have believed, a rare mystical experience, but a frequent expression of our most basic human impulses. Shaman and scientist, medium and poet, prophet and philosopher, all venture forth in quest of visionary truths to transform and renew the world. Yet Torrance is not trying to reduce the quest to an "archetype" or "monomyth." Instead, he presents the full diversity of the quest in the myths and religious practices of tribal peoples throughout the world, from Oceania to India, Africa, Siberia, and especially the Americas. In theorizing about the quest, Torrance draws on thinkers as diverse as Bergson and Piaget, van Gennep and Turner, Pierce and Popper, Freud, Darwin, and Chomsky. This is a book that will expand our knowledge—and awareness—of a fundamental human activity in all its fascinating complexity.
Perturbing the Organism
Overlooked in the early accounts was that all organisms face many additional types of natural challenges and obstacles in their efforts to survive and reproduce: for example, they must fight or escape predators, replenish diminished food supplies, and anticipate, seasonal changes of climate. Weiner's survey of the literature shows that much progress has been made in understanding the effects of exposing animals to these kinds of naturally occurring stressful experiences and their varied outcomes. Under such conditions there appear patterns of integrated behavioral and physiological responses that are exquisitely attuned to the experience. He carefully assesses the research on the ways in which neural circuits and peptidergic mechanisms in the brain generate and integrate these patterns. In addition, he presents new concepts about the perturbation of subsystems, including biological clocks, which may, or may not, lead to disease or ill-health.
Common Ground
Common Ground explores the shifting relationship between human society and the landscapes that bear it. Examining the changing understandings of the natural world and its management and exploitation, environmental activist Mark Everard presents solutions in the nature of ecosystem services. Notwithstanding our total dependence on the Earth's natural resources, the relationship between humanity and the land has shifted significantly and frequently throughout our tenure, brief as it is relative to the evolution of planetary life. Appropriating increasing proportions of nature's resources to meet our shifting and growing demands, we have been degrading the quality and extent of ecosystems, nearly destroying their capacities to meet the needs of a burgeoning population. The book offers a fresh and vital whole-system approach to the key under-pinning the issue of sustainability. Everard looks ahead to what is required to live sustainably, respecting the central role of landscapes in supporting human wellbeing into the long-term future.
Doctors and Discoveries
Traces the history of western medicine through the lives of its major contributors, profiling such well-known figures as Hippocrates and Louis Pasteur, as well as lesser-known scientists including Elle Metchnikoff and Samuel Hahnemann.
