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These proceedings include the Technical Evaluation Report, a tribute to Dr. Henning E. von Gierke, Director Emeritus, Wright-Patterson Air Force Base (WPAFB), OH, three Keynote Addresses and 32 invited papers of a Specialists' Meeting sponsored by the NATO/RTO Human Factors and Medicine Panel. It was held at WPAFB from 26-28 October 1998. Significant advances have been made in modelling human physical and physiological responses to extreme environments. Technological advances in computer speed and power have made modelling a feasible research and design tool. Computer simulations are being used extensively for predicting human physical and physiological responses, for reducing testing requir...