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Cholecystokinin and Anxiety: From Neuron to Behavior
This book is about the role of cholecystokinin (CCK) in the neurobiology of anxiety and panic attacks. An up-to-date review of the topic is given in a multidisciplinary perspective ranging from neurochemistry to human behavior. This volume is equally informative to basic and clinical scientists.
Interleukin-10
The presented information reflects a state-of-the-art summary of the pleiotropic effects of IL-10 in vitro and in vivo and will contribute to our understanding of the role of ILj-10 in the immune system and its potential clinicial utility in the near future. The book contains chapters in which the in vitro biological effects of IL-10 on both mouse and human lymphoid and myeloid cells are reviewed. In addition, the role of IL-10 in transplantation, parasite infections, inflammation, infectious diseases and bone formation is described. The effects of IL-10 in vivo are presented, describing an IL-10 transgenic mouse model, the IL-10 "knock-out" mouse, and the capacity of IL-10 to prevent lethal toxic shock in mice.
The Nucleosome
This is the first in a series of volumes concerning the properties of the eukaryotic nucleus. Contributions from several of the most active laboratories are brought together to present a focused overview of a selected aspect of nuclear structure and function.
Protein Targeting to Mitochondria
A large number of newly-synthesized polypeptides must cross one or several intracellular membranes to reach their functional locations in the eukaryotic cell. The mechanisms of protein trafficking, in particular the post-translational targeting and membrane translocation of proteins, are of fundamental biological importance and are the focus of intensive research world-wide. For more than 15 years, mitochondria have served as the paradigm organelle system to study these processes. Although key questions, such as how precisely proteins cross a membrane, still remain to be answered, exciting progress has been made in understanding the basic pathways of protein import into mitochondria and the ...
Pharmacotherapy for Mood, Anxiety, and Cognitive Disorders
Our limited knowledge of the pathophysiology underlying mood disorders contrasts sharply with the efficacy of the treatment modalities developed over the past decades. There has been an explosion of new antidepressant and anxiolytic medications, as well as mood stabilizers and compounds that aim to improve cognition. Although treatment success is still not optimal, pharmacotherapy for mood disorders and cognitive disorders is effective and is improving. Pharmacotherapy for Mood, Anxiety, and Cognitive Disorders takes a critical look at the medications available for treating mood, anxiety and cognitive disorders; their relevance to pathobiology and underlying mechanisms; and their limitations...
The Language of Medicine E-Book
Effectively master medical terminology with Davi-Ellen Chabner's The Language of Medicine, 13th Edition. Centering on Chabner's proven method of learning medical terms by studying them in the context of the human body, this highly praised and bestselling text helps individuals of all educational backgrounds easily understand and remember important medical terminology by incorporating easy-to-follow explanations, relevant examples, and countless reinforcement exercises. This new edition also features additional clinical practice exercises; more medical procedure photos; timely content on immunity and vaccines, infection control, advances in cardiology, cancer research, emerging orthopedic tre...
Pre-mRNA Processing
he past fifteen years have seen tremendous growth in our understanding of T the many post-transcriptional processing steps involved in producing func tional eukaryotic mRNA from primary gene transcripts (pre-mRNA). New processing reactions, such as splicing and RNA editing, have been discovered and detailed biochemical and genetic studies continue to yield important new insights into the reaction mechanisms and molecular interactions involved. It is now apparent that regulation of RNA processing plays a significant role in the control of gene expression and development. An increased understanding of RNA processing mechanisms has also proved to be of considerable clinical importance in the pa...
c-Myc Function in Neoplasia
1. 1 SCOPE OF BOOK n explosion of novel findings in the past decade has contrib A uted to the great progress toward understanding the biology of human cancers. Much of this progress can be attributed to our abil ity to dissect many biological processes at the molecular level. Most spectacular is the technology of molecular biology that allows identi fication and characterization of genes that participate in the genesis of human cancers. Three major groups of genes appear to play out the drama of cancer development: tumor suppressor genes, mis match repair genes, and oncogenes. The tumor suppressor genes 1 encode products that are inhibitory to cell proliferation. The loss of these inhibitors...
Intergenerational Mobility
This volume presents a complex portrait of the interrelationships among parents’ marital status and education, child gender, and the nature and success of children’s transitions into adulthood. The first three chapters focus on differences in parents’ investments in their children, while the final three chapters focus directly on intergenerational income mobility.
