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Oncogenes as Transcriptional Regulators
1 Myc Structure and Function.- 2 The ETS Family of Transcriptional Regulators.- 3 myb Proto-Oncogene Product as a Transcriptional Regulator.- 4 The v-erbA Oncogene.- 5 Rel Proteins and Their Inhibitors: A Balancing Act.- 6 Structure/Function and Oncogenic Conversion of Fos and Jun.
RNA Tumor Viruses, Oncogenes, Human Cancer and AIDS: On the Frontiers of Understanding
We stand today on the threshold of a new understanding of cancer. Primarily through the powerful tools of molecular biology, unified hypotheses explaining the origins of the disease are emerging and rapidly being validated. This volume, which presents the latest findings from laboratories throughout the world on the role of RNA tumor viruses in cancer, is a celebration of these achievements and a prediction of further progress leading ultimately to the control of the disease. It is important in this context to recall the natural history or life cycle of RNA cancer virology. From the earliest days of the science, when viruses were first recognized as distinct biologic agents of etiologic sign...
Advanced Research on Animal Cell Technology
Proceedings of the NATO Advanced Research Workshop, Brussels, Belgium, September 21-24, 1987
Orphan Drugs and Rare Diseases
This book provides an up-to-date monograph on the drug discovery and regulatory elements of therapuetics used to treat rare or "orphan" diseases.
Annual Report
None
Universal Laws of Nature and Cells
The structure and metabolism of prokaryotic and eukaryotic cells reveals their nature and evolution, which can lead to new treatments for infectious and malignant diseases. Goran Indjic, a physician and clinical microbiologist, shares a detailed analysis of the phenomena of prokaryotic and eukaryotic cells in the book. Taking an innovative approach, he upends contemporary literature in the field. Relying on biology, philosophy, other scientific disciplines, and even art, Indjic offers fresh ideas and experiments for investigating the nature of prokaryotic and eukaryotic cells. According to this new approach, basic structures of prokaryotic and eukaryotic cells consist of polypeptides that bu...
Malignant Cell Secretion
First Published in 1990, this book offers a full, comprehensive guide into the nature of cells. Carefully compiled and filled with a vast repertoire of notes, pictures, and references this book serves as a useful reference for Students of Medicine, Microbiology, and other practitioners in their respective fields.
JAK-STAT Signaling in Diseases
JAK-STAT pathway is one of the few signal transduction pathways that transduce signals involved in multiple homeostatic biological processes including cell differentiation and proliferation, cell death, hematopoiesis and immune responses. JAK-STAT is an elegant pathway that is relatively simple and evolutionary conserved as gene expression is regulated by external parameters. Activated by growth factors or cytokines, this signal transduction cascade regulates the transcription of genes at the nucleus. Mutations and polymorphisms in JAK-STAT pathway are associated with inflammatory diseases and cancers that could impede regular homeostasis. Features: Details activation and microRNA-mediated r...
