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Handbook of Proteolytic Enzymes
Extensively revised and updated, the new edition of the highly regarded Handbook of Proteolytic Enzymes is an essential reference for biochemists, biotechnologists and molecular biologists. Edited by world-renowned experts in the field, this comprehensive work provides detailed information on all known proteolytic enzymes to date. This two-volume set unveils new developments on proteolytic enzymes which are being investigatedin pharmaceutical research for such diseases as HIV, Hepatitis C, and the common cold. Volume I covers aspartic and metallo petidases while Volume II examines peptidases of cysteine, serine, threonine and unknown catalytic type. A CD-ROM accompanies the book containing f...
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Drug Development for Parasite-induced Diarrheal Diseases
One of the top four contributors to the global burden of disease is diarrheal infections. Intestinal parasites are major causes of morbidity and mortality associated with diarrheal diseases in both the developed and developing world. Amebiasis is responsible for 50 million cases of invasive disease and 70,000 deaths annually in the world. Giardiasis has an estimated worldwide prevalence of 280 million cases annually. In developed countries, Giardia lamblia infects about 2% of adults and 6-8% of children. The prevalence of G. lamblia infection is generally higher in developing countries, ranging from 3% to 90%. Furthermore, giardial infections contribute substantially to the 2.5 million annua...
Poverty and Neglected Tropical Diseases in the American Rural South
In Poverty and Neglected Tropical Diseases in the American Rural South, Christine Crudo Blackburn and Macey T. Lively study regions of the United States rarely acknowledged by the average American. These are regions of extreme poverty in the rural American South where a mixture of historical discrimination, structural discrimination, lack of opportunities, and decaying infrastructure conspire to create an environment conducive to chronic, debilitating diseases known as Neglected Tropical Diseases (NTDs). Blackburn and Lively explore the conditions that allow NTDs to thrive in a wealthy nation like the United States when such diseases are typically associated with the poorest communities in Africa, Asia, and South America. Poverty and Neglected Tropical Diseases pulls back the curtain on the reality of poverty and disease in America and tell the story of failing sanitation infrastructure, the lack of clean water, the inability to access healthcare, and the lack of financial security through the eyes of those living it every day.
Global Health Training in Graduate Medical Education
Global Health Training in Graduate Medical Education is a guide to help medical schools, residency programs, students, residents, fellows, educators and allied health professionals create, expand and improve global health education. Investigate the history of global health work, learn from the experience of established programs and health care leaders, seek out new educational resources, and consider the ethical implications of health work in communities at home and abroad.
Cysteine Proteases of Pathogenic Organisms
Cysteine proteases expressed by pathogenic organisms play key roles in virulence including host entry, feeding and suppression of host immune responses. This book gives comprehensive coverage to all aspects of pathogen cysteine proteases and brings together numerous scientific advances which have been made over many years. Thus, the biochemistry, molecular biology and structure‐function relationships of these important pathogen enzymes are covered in detail. Written by leading researchers from Europe, Australia and North America, this book is essential reading for students and professionals interested in human medicine and infectious disease research.
