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An essential guide for every woman over the age of 30, this book focuses on one of the least understood, and most ignored, aspects of the aging process--the cognitive problems that accompany the decline of estrogen levels.
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The endothelial cells of the cerebral vasculature constitute, together with perivascular elements (astrocytes, pcricytes, basement membrane), the blood-brain barrier (BBB), which strictly limits and specifically controls the exchanges between the blood and the cerebral extracellular spacc.The existence of such a physical, enzymatic, and active barrier isolating the central nervous system has broad physiological, biological, pharmacological, and patho logical consequences, most of which are not yet fully elucidated. The Cerebral Vascular Biology conference (CVB '95) was organized and held at the "Carre des Sciences" in Paris on July I 0-12, 1995. Like the CVB '92 conference held in Duluth, Mi...
The last Kindling Conference was organized by Dr. Juhn Wada and held at the Univer sity of British Columbia, Vancouver, B. C. , in 1989. In the intervening years, research on kin dling has proceeded at an explosive pace and significant advances have been made in our understanding of the molecular biological, anatomical, and physiological substrates of kin dling, as well as in our appreciation of the age-dependent effects and complex behavioral consequences of kindling, its sensitivity to drugs, and its relevance to the clinical epilepsies. In order to review these developments and to provide researchers with an opportunity to in teract face to face and discuss the issues that preoccupy us al...
''Emphasis on new issues and emerging concepts insures that the information presented is still timely...A compelling source of information on recent research in the field.'' ---Journal of Chemical Neuroanatomy, May 1997
This volume, The Basal Ganglia V, is derived from proceedings of the fifth Triennial Meeting of the International Basal Ganglia Society (IBAGS). The Meeting was held from 23-26 May, 1995, at Nemuno-Sato, in the Mie Prefecture of central Japan, not far from the traditional birth place of the country. As at previous Meetings, our aim was to hear and discuss new ideas and data on the Basal Ganglia. About one hundred papers were presented, on platform or as posters. We had valuable talks, stimulating discussions, and agreeable social contacts. Although just before this Meeting, there were several unusual accidents in Japan, a big earthquake in the Kobe area, not far from the Meeting place, and t...
JOSEPH MEITES The idea that the endocrine system is involved in aging processes is as old as the beginnings of endocrinology. The first endocrine experiment related to aging was reported by Brown-Sequard, who is usually re garded as the "father of endocrinology. " In 1889, at the age of 72 years, he reported that he had succeeded in rejuvenating himself by injections of testicular extracts from dogs and guinea pigs. Although the favorable effects observed may have been due mainly to the powers of auto suggestion, his reports created a considerable interest in endocrinology and its relation to aging, and eventually led to the use of estrogens for treating certain pre-and postmenopausal sympto...