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Hydrogels
The studies on Biohydrogels have had a rapid, exponential evolution in the last decades. This book is the result of an International conference gathering the most recent results in this field.
Drug Design
Drug Design, Volume X covers promising and current developments in drug design. The book discusses procedures as applied in the practice of drug design; the structural aspects of the structure-activity relationships of neuroleptics; and promising perspectives in the highly actual field of bioactive peptides. The text also describes the application of the dynamic systems analysis to the antihypertensive drug action; polymeric drug delivery systems; and the design of biocompatible polymers. The structure-activity relationships of insect repellents as a basis for the design of such agents, as well as the approaches to the multivariate data analysis in structure-activity relationships, which is an essential aspect of drug design, are also encompassed. Chemists, pharmacologists, bioengineers, and people involved in drug design and manufacture will find the book invaluable.
Materiomics: Multiscale Mechanics of Biological Materials and Structures
Multiscale mechanics of hierarchical materials plays a crucial role in understanding and engineering biological and bioinspired materials and systems. The mechanical science of hierarchical tissues and cells in biological systems has recently emerged as an exciting area of research and provides enormous opportunities for innovative basic research and technological advancement. Such advances could enable us to provide engineered materials and structure with properties that resemble those of biological systems, in particular the ability to self-assemble, to self-repair, to adapt and evolve, and to provide multiple functions that can be controlled through external cues. This book presents material from leading researchers in the field of mechanical sciences of biological materials and structure, with the aim to introduce methods and applications to a wider range of engineers.
Functional Biomaterials
Discusses design chemistry, modification, and processing of biomaterials Describes the efficacy of biomaterials at various scales for biological response and drug delivery Demonstrates technological advances from conventional to additive manufacturing Covers future of biofabrication and customized medical devices
Pathogenesis of Wound and Biomaterial-Associated Infections
Despite the recent advances in medical treatment, patients suffering from wounds such as burns or receiving surgical implants are still in great danger of infection. This has called attention to the need for better understanding of infections at the molecular level. Scientists from various disciplines summarize our knowledge today and investigate how methods to avoid wound and biomaterial-associated infections can be developed. These methods include new antibiotics, surgical strategies to prevent infection, and ways to stimulate the immune system and the tissue healing process. Specific topics include: the definition of microbial cell surface determinants important for adhesion to graft; the definition of extracellular bacterial enzymes and toxins involved in tissue breakdown and the local spread of infection; the prevention of the systemic spreading of infection with immunoglobulins and antibiotics; and the problem of multiple antibiotic resistance in most versatile pathogens.
Advances in Biomedical Polymers
This book is derived from a Symposium held at the 190th National American Chemical Society Meeting, which was held in the Fall of 1985, in Chicago, and was sponsored by the Division of Polymeric Materials: Science & Engineering. This Symposium was, in turn, a follow-up on an earlier one held in Houston, TX, in the Spring of 1980, which was pub lished as the book ·Biomedical and Dental Applications of Polymers· [Plenum Press, New York, 1981]. In that earlier book, our opening Preface passage quoted King David, ·1 will praise Thee; for I am fearfully and made . •• • (Psalm 139:14). As we noted five years ago, sickness wonderfully of many types does occur in our wonderfully made bodies...
Controlled Release of Bioactive Materials
Controlled Release of Bioactive Materials is a collection papers that deal with the study of controlled release applications in drugs and other pharmacological products and processes. The text covers topics such as the theory and practice of controlled drug delivery from bioerodible polymers, biodegradable drug delivery systems from aliphatic polyesters, and the applications of osmotic drug delivery. Also covered are topics such as the application of polymers for the sustained release of macromolecules, controlled transdermal delivery, and the use of hydrogel devices for the controlled release of steroid hormones. The book is recommended for pharmacologists and doctors who would like to know more about advancements in the field of controlled release applications and its uses in healthcare, especially in pharmacology.
Surface Design: Applications in Bioscience and Nanotechnology
This carefully selected balance of tutorial-like review chapters and advanced research covers hot topics in the field of biointerfaces, biosensing, nanoparticles at interfaces, and functionalized quantum dots. It also includes chapters arising from non-published work with topics such as surface design and their applications, as well as new developments in analytical tools for materials science and life science. Based on the very close and complementary collaboration of three distinguished leading research groups, this book highlights recent advances in the field ranging from synthesis and fabrication of organic and polymeric materials, surface and interface science to advanced analytical met...
Advances in Drug Delivery Systems, 6
Advances in Drug Delivery Systems, 6 focuses on the progress in drug delivery systems as manifested in the fields of international pharmaceutics, polymer science, biotechnology, molecular biology, and cell biology. The selection first tackles biologically engineered microstructures and approaches to targeting bioactive compounds. Discussions focus on therapeutic efficiency of fatty acylated antiviral antibodies; effect of artificial fatty acylation on protein binding and uptake; and controlled release of proteins from lipid microcylinders. The text then elaborates on mucosal delivery of macromolecules and targeted delivery of diagnostic agents by surface-modified liposomes. The book examines...
