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Focusing on the practical use of N-Acetyl-Cysteine (NAC) in medicine, this book provides a comprehensive review of the basic biological and clinical studies documenting its benefits in treating medical disease. NAC is perhaps best known as an antidote for acetaminophen, but its therapeutic effect in a wide range of medical diseases has recently been realized. In addition to its well recognized use in radiological contrast prophylaxis for renal disease and pulmonary disorders, studies have suggested significant promise in psychiatric and neurological disorders such as addiction, Alzheimer’s disease, ataxia, autism, bipolar disorder, depression, epilepsy, neuropathy, obsessive-compulsive dis...
An improved understanding of the interactions between nanoparticles and plant retorts, including their uptake, localization, and activity, could revolutionize crop production through increased disease resistance, nutrient utilization, and crop yield. This may further impact other agricultural and industrial processes that are based on plant crops. This two-volume book analyses the key processes involved in the nanoparticle delivery to plants and details the interactions between plants and nanomaterials. Potential plant nanotechnology applications for enhanced nutrient uptake, increased crop productivity and plant disease management are evaluated with careful consideration regarding safe use,...
This book offers a broad overview of the concepts and research findings in immunometabolism. The immune system is made up of numerous different cell types, pathways, and components that must be able to respond rapidly to a pathogen or cancer, but must also remain quiescent in the absence of challenges. Immune cells rely on metabolic pathways to adapt to changing environments and stimuli. Additionally, these cells can be modified in function or fate by fluctuations in available nutrients. The chapters in this book describe ways in which immune cells utilize and are regulated by metabolic pathways. Topics include how immune-cell metabolism shapes immune homeostasis, and how dysregulation of th...
This book covers physiologic, metabolic and molecular imaging for gliomas. Gliomas are the most common primary brain tumors. Imaging is critical for glioma management because of its ability to noninvasively define the anatomic location and extent of disease. While conventional MRI is used to guide current treatments, multiple studies suggest molecular features of gliomas may be identified with noninvasive imaging, including physiologic MRI and amino acid positron emission tomography (PET). These advanced imaging techniques have the promise to help elucidate underlying tumor biology and provide important information that could be integrated into routine clinical practice. The text outlines cu...
Vision is the most important sense in higher mammals. The retina is the first step in visual processing and the window to the brain. It is not surprising that problems arising in the retina lead to moderate to severe visual impairments. We offer here a collection of reviews as well as original papers dealing with various aspects of retinal function as well as dysfunction. New approaches in retinal research are described, such as the expression and localization of the endocannabinoid system in the normal retina and the role of cannabinoid receptors that could offer new avenues of research in the development of potential treatments for retinal diseases. Moreover, new insights are offered in advancing knowledge towards the prevention and cure of visual pathologies, mainly AMD, RP, and diabetic retinopathy.
Highlighting recent advances in our understanding of breast cancer, this book is intended for a wide audience as a reference book. Included are reviews of genetics, epigenetics, various aspects of cell and molecular biology, and several other areas of breast cancer that are aimed at determining new intervention sites for treatments and cures of the disease. The chapters are written by internationally recognized experts and include reviews of key topics in breast cancer research. Each chapter highlights the new aspects of specific research topics and the various impacts of designing new strategies as well as identifies new targets for therapeutic intervention. The topics addressed are selected to be of interest to patients, scientists, students, teachers, and anyone else interested in expanding their knowledge of breast cancer imaging, diagnostics, therapeutics, or basic biomedical research on breast cancer.
Vols. for 1963- include as pt. 2 of the Jan. issue: Medical subject headings.
The miniaturization of industrial products is a global trend. Metal forming technology is not only suitable for mass production and excellent in productivity and cost reduction, but it is also a key processing method that is essential for products that utilize advantage of the mechanical and functional properties of metals. However, it is not easy to realize the processing even if the conventional metal forming technology is directly scaled down. This is because the characteristics of materials, processing methods, die and tools, etc., vary greatly with miniaturization. In metal micro forming technology, the size effect of major issues for micro forming have also been clarified academically....
Arsenic Pollution summarizes the most current research on the distribution and causes of arsenic pollution, its impact on health and agriculture, and solutions by way of water supply, treatment, and water resource management. Provides the first global and interdisciplinary account of arsenic pollution occurrences Integrates geochemistry, hydrology, agriculture, and water supply and treatment for the first time Options are highlighted for developing alternative water sources and methods for arsenic testing and removal Appeals to specialists in one discipline seeking an overview of the work being done in other disciplines
This is a Special Issue of Metals devoted to aspects of Advances in Mineral Processing and Hydrometallurgy. This includes a global call for article submissions that also included Characterization along with Recycling and Waste Minimization. As such, both primary and recycled aspects will be considered. Possible specific topics included Mineralogy, Geometallurgy, Thermodynamics, Kinetics, Comminution, Classification, Physical Separations, Liquid-Solid Separations, Leaching, Solvent Extraction, Ion Exchange, Activated Carbon, Precipitation, Reduction, Process Economics and Process Control. Suggested application areas were in Gold, Silver, PGM's, Aluminum, Copper, Zinc, Lead, Nickel, and Titanium. Critical Metals articles on topics such as Lithium, Antimony Tellurium, Gallium, Germanium, Cobalt, Graphite, Indium, and Rare Earth were also welcome. As such, this Special Issue of Metals was well supported by diverse submissions and the final publication of high-quality peer-reviewed articles.