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Adaptation Biology and Medicine
It has become amply clear that all live forms on Earth are the products of the constituent genes expressed under the influence of continuously changing natural environment. By the same token, gene expression is known to be modified by our (or by the modern) environment inclusive of factors such as gravity, altitude, temperature, atmospheric pressure and air quality, physical conditioning as well as nutrition and/or lifestyle. Life would not survive without recruiting endogenous adaptive mechanisms responsive to challenging environmnetal factors, Biology of adaptation as well as application of this knowledge has been discussed in both health and disease conditions such as cardiac ischemia and cardiomyopathies, stroke, dementia, Alzheimer's, cancer, metal toxicity, etc. The book will be of great interest to experimental biologists and health professionals dealing with benefits and failures of physiological and pathophysiological adaptations. It will also serve as an important source of information for young scientists, postdocs and students.
Exosomes in Cardiovascular Diseases
The book provides and intensive overview on exosomes in cardiovascular diseases, its potential as biomarkers, as well as pathological and therapeutic effects. It firstly describes the general aspects of exosomes including the definition, formation and secretion of exosomes and highlight their roles as biomarkers and pathological and therapeutic effects in cardiovascular diseases as well. Secondly, basic aspects of exosomes including the purification methods of exosomes, exosomes content, and functional roles of the cardiovascular exosomes are summarized. Thirdly, exosomes as biomarkers of cardiovascular diseases are overviewed including their roles in diagnosis, prognosis and reaction to therapy. Fourthly, pathological effects of exosomes and therapeutic effects of exosomes are highlighted. Finally, future prospects of exosomes in cardiovascular research would be provided. This is an essential reference for researchers working in cell biology and regeneration, as well as clinicians such as cardiologist.
The Palgrave Handbook of European Media Policy
Containing state-of-the-art contributions on the various domains of European media policies, this Handbook deals with theoretical approaches to European media policy: its historical development; specific policies for film, television, radio and the Internet; and international aspects of the fragmented policy domain.
Mitochondrial Dynamics in Cardiovascular Medicine
This text covers the basic principles of mitochondrial dynamics in cardiovascular medicine, with particular emphasis on their functional roles in physiology and disease. The book will include articles pertaining to mitochondrial fitness on a global basis, providing therefore an update on the progress made in several aspects in the field. Thus, it will assist scientists and clinicians alike in furthering basic and translational research. Organized in sections focusing on: basic science, mitochondrial dysfunction in cardiac disorders, in vascular disorders, in metabolic disorders, in kidney disease, therapeutic challenges and options, this essential volume fills imperative gaps in understanding and potentially treating several cardiovascular disorders.
Zymography
This detailed volume examines the latest techniques and protocols associated with zymography, the practice of detecting enzyme activity on electrophoretic gels. Sections cover subjects such as endopeptidase zymography, reverse zymography & in situ zymography, 2D zymography, as well as a variety of special cases. Written in the highly respected Methods in Molecular Biology series format, chapters include brief introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Comprehensive and practical, Zymography: Methods and Protocols serves as an ideal aid for a broad array of researchers from the fields of biological and medicinal science, as well as scientists working in clinical and diagnostic medicine, medical genetics, agricultural entomology, genetic monitoring of environmental pollution, and forensic science.
Polyphenols: Mechanisms of Action in Human Health and Disease
Polyphenols: Mechanisms of Action in Human Health and Disease, Second Edition describes the mechanisms of polyphenol antioxidant activities and their use in disease prevention. Chapters highlight the anti-inflammatory activity of polyphenols on key dendritic cells, how they modulate and suppress inflammation, and how they are inactivated or activated by metabolism in the gut and circulating blood. Polyphenols have proven effective for key health benefits, including bone health, organ health, cardiac and vascular conditions, absorption and metabolism, and cancer and diseases of the immune system. They are a unique group of phytochemicals that are present in all fruits, vegetables and other plant products. This very diverse and multi-functional group of active plant compounds contain powerful antioxidant properties and exhibit remarkable chemical, biological and physiological properties, including cancer prevention and cardio-protective activities. - Expands coverage on green tea, cocoa, wine, cumin and herbs - Outlines their chemical properties, bioavailability and metabolomics - Provides a self-teaching guide to learn the mechanisms of action and health benefits of polyphenols
Computer Games and New Media Cultures
Digital gaming is today a significant economic phenomenon as well as being an intrinsic part of a convergent media culture in postmodern societies. Its ubiquity, as well as the sheer volume of hours young people spend gaming, should make it ripe for urgent academic enquiry, yet the subject was a research backwater until the turn of the millennium. Even today, as tens of millions of young people spend their waking hours manipulating avatars and gaming characters on computer screens, the subject is still treated with scepticism in some academic circles. This handbook aims to reflect the relevance and value of studying digital games, now the subject of a growing number of studies, surveys, conf...
Converging Media, Diverging Politics
What purpose does the news media serve in contemporary North American society? In this collection of essays, experts from both the United States and Canada investigate this question, exploring the effects of media concentration in democratic systems. Specifically, the scholars collected here consider, from a range of vantage points, how corporate and technological convergence in the news industry in the United States and Canada impacts journalism's expressed role as a medium of democratic communication. More generally, and by necessity, Converging Media, Diverging Politics speaks to larger questions about the role that the production and circulation of news and information does, can, and should serve. The editors have gathered an impressive array of critical essays, featuring interesting and well-documented case studies that will prove useful to both students and researchers of communications and media studies.
Understanding Autism
Taking an all-inclusive look at the subject, Understanding Autism: From Basic Neuroscience to Treatment reviews state-of-the-art research on the diagnosis, treatment, and prevention of autism. The book addresses potential mechanisms that may underlie the development of autism and the neural systems that are likely to be affected by these molecular,
Network Journalism
Drawing on current theoretical debates in journalism studies, and grounded in empirical research, Heinrich here analyzes the interplay between journalistic practice and processes of globalization and digitalization. She argues that a new kind of journalism is emerging, characterized by an increasingly global flow of news as well as a growing number of news deliverers. Within this transformed news sphere the roles of journalistic outlets change. They become nodes, arranged in a dense net of information gatherers, producers, and disseminators. The interactive connections among these news providers constitute what Heinrich calls the sphere of "network journalism."
