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Current Catalog
First multi-year cumulation covers six years: 1965-70.
Management Andragogics 2
At a time when managers often provide fodder for unseemly headlines, and some are even compared unflatteringly with locusts, today’s business leaders are called upon as never before to demonstrate the moral justification for their activities, and to ensure that it is understood by all the key stakeholders of a company. What is required is nothing less than a management renaissance, based on a thoroughgoing concept of corporate leadership; there is no less a need for decision makers who hold themselves to the highest standards, with a positive perception of their fu- tion as agents of dissemination, and who are committed to the good not only of “their” firm, but also of society in gener...
Profiles of Drug Substances, Excipients and Related Methodology
Profiles of Drug Substances, Excipients and Related Methodology
Methods for Analysing and Reporting EQ-5D Data
This open access book is the first published guide about how to analyse data produced by the EQ-5D, one of the most widely used Patient Reported Outcomes questionnaires world wide. The authors provide practical, clear and comprehensive guidance in five concise chapters. Following an overview of the EQ-5D and its analysis, we describe how the questionnaire data – the EQ-5D profile and EQ VAS – can be analysed in different ways to generate important insights into peoples’ health. We then show how the value sets which accompany the EQ-5D can be applied to summarise patients’ data. The final chapter deals with advanced topics, including the use of Minimally Important Differences, case-mix adjustment, mapping, and more. This book is essential for those new to analyzing EQ-5D data and will be also be valuable for those with more experience. The methods can be applied to any EQ-5D instrument (for example, the three- and five-level and Youth versions) and many of the methods described will be equally relevant to other Patient Reported Outcomes instruments.
Serotonin
This volume represents the proceedings ofthe invited lectures ofthe first International Symposium on "Serotonin from Cell Biology to Pharmacology and Therapeutics" which was held in Florence on March 29 -Aprill, 1989. This meeting, held under the co-sponsorship of the Serotonin Club and the Fondazione Giovanni Lorenzini, represents the first attempt to bring together scientists fascinated by the complexity of the action of 5-hydroxytryptamine throughout the body and in various species. Hence this volume provides the reader with the unique overview of the sources, effects, receptors, physiological actions and pathological role of Serotonin. As such it will be of interest not only to the perso...
Aspergillus and Aspergillosis
Species of aspergilli are common in man's environment and are responsible for a wide spectrum of human and animal disease, ranging in animals from mycotic abortion to aflatoxicosis and in humans from localized colonization of the ear or skin to life-threatening systemic infection of neutropenic patients. In recent times, invasive aspergillosis has become increasingly important as a cause of morbidity and death, initially in patients receiving immunosuppression prior to organ transplantation, and latterly in haematologic patients rendered neutropenic by underlying disease or chemotherapy. In some centres, the condition has been recorded in more than 40% of patients dying with acute leukaemia....
The Lennox Legacy
The Lennox Legacy: The history of the CSIRO Laboratory at 343 Royal Parade Parkville records many of the events and incidents associated with the genesis and development of the Division of Protein Chemistry over a period of more than fifty years. This book has been titled in honour of Dr Francis Gordon Lennox, the Laboratory's founder and a man who believed that science has an important part to play in bettering the well-being of all Australians. His vision, over the years, of the critical importance of protein chemistry to Australian science and industry, was central to the Laboratory's national and international achievements. The book has been written three parts: *Part 1 attempts to trace...
Antiviral Drug Strategies
By focusing on general molecular mechanisms of antiviral drugs rather than therapies for individual viruses, this ready reference provides the critical knowledge needed to develop entirely novel therapeutics and to target new viruses. It begins with a general discussion of antiviral strategies, followed by a broad survey of known viral targets, such as reverse transcriptases, proteases, neuraminidases, RNA polymerases, helicases and primases, as well as their known inhibitors. The final section contains several cases studies of recent successful antiviral drug development. Edited by Erik de Clercq, the world authority on small molecule antiviral drugs, who has developed more new antivirals than anyone else.
