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Bone metastasis in the milieu of Osteoimmunology
Bone metastases are common in many cancers and associated with skeletal-related events such as spinal cord compression, fractures, pain, disability, and impaired quality of life. Bone metastasis is most prominent in breast, prostate, and lung cancer patients and is the leading cause of cancer-associated death. Osteoblasts and osteoclasts control each other’s functions to maintain normal bone homeostasis. In addition, bone remodeling is governed by the balanced activity of the bone and immune cells. Bone metastasis is a multistage process, and the bone microenvironment influences the seeding and colonization of the disseminated cancer cells. Disruption of bone homeostasis and immune population provides fertile soil to facilitate cancer cell seeding. Despite the advancement of our understanding to treat primary tumors, most of the treatments for bone metastasis are palliative. Proper understanding of the immune component of the bone and their involvement in bone metastasis niche formation will help to explore future directions of bone metastasis research.
ICIDSSD 2020
The International Conference on ICT for Digital, Smart, and Sustainable Development (ICIDSSD’20) aims to provide an annual platform for the researchers, academicians, and professionals from across the world. ICIDSSD’20, held at Jamia Hamdard, New Delhi, India, is the second international conference of this series of conferences to be held annually. The conference majorly focuses on the recent developments in the areas relating to Information and Communication Technologies and contributing to Sustainable Development. ICIDSSD’20 has attracted research papers pertaining to an array of exciting research areas. The selected papers cover a wide range of topics including but not limited to Su...
Finance, Accounting and Law in the Digital Age
This book focuses on understanding Innovation in the Financial Services Sector. The collection of contributions gathered in the book highlights the importance of technology contexts that pertain to Finance, accounting, and the law arena. The respective chapters address topics such as Economic development, social entrepreneurship, Online Behaviour, Digital entrepreneurship, and Islamic banks. All contributions are based on the latest empirical and theoretical research and provide key findings and concrete recommendations for scholars, entrepreneurs, organizations, and policymakers.
AACR 2022 Proceedings: Part B April 11-13
The AACR Annual Meeting is the focal point of the cancer research community, where scientists, clinicians, other health care professionals, survivors, patients, and advocates gather to share the latest advances in cancer science and medicine. From population science and prevention; to cancer biology, translational, and clinical studies; to survivorship and advocacy; the AACR Annual Meeting highlights the work of the best minds in cancer research from institutions all over the world.
Women in Cytokines and Soluble Mediators in Immunity
We are delighted to present the inaugural Frontiers in Immunology “Women in Cytokines and Soluble Mediators in Immunity” series of article collections. At present, less than 30% of researchers worldwide are women. Long-standing biases and gender stereotypes are discouraging girls and women away from science-related fields, and Science, Technology, Engineering and Mathematics (STEM) research in particular. Science and gender equality are, however, essential to ensure sustainable development as highlighted by UNESCO. In order to change traditional mindsets, gender equality must be promoted, stereotypes defeated, and girls and women should be encouraged to pursue STEM careers.
Adios, America
A National Bestseller! Ann Coulter is back, more fearless than ever. In Adios, America she touches the third rail in American politics, attacking the immigration issue head-on and flying in the face of La Raza, the Democrats, a media determined to cover up immigrants' crimes, churches that get paid by the government for their "charity," and greedy Republican businessmen and campaign consultants—all of whom are profiting handsomely from mass immigration that’s tearing the country apart. Applying her trademark biting humor to the disaster that is U.S. immigration policy, Coulter proves that immigration is the most important issue facing America today.
The Responsible Software Engineer
You might expect that a person invited to contribute a foreword to a book on the 1 subject of professionalism would himself be a professional of exemplary standing. I am gladdened by that thought, but also disquieted. The disquieting part of it is that if I am a professional, I must be a professional something, but what? As someone who has tried his best for the last thirty years to avoid doing anything twice, I lack one of the most important characteristics of a professional, the dedicated and persistent pursuit of a single direction. For the purposes of this foreword, it would be handy if I could think of myself as a professional abstractor. That would allow me to offer up a few useful abs...
