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Brain Organoid Research
This volume explores multiple methods and approaches used to generate human brain and neuroretinal organoids to address fundamental questions in human brain research. The chapters in this book cover topics such as self-organizing brain organoids with ventricles amenable to injection and electroporation; visualization of 3D organoids though the latest advancements in microscopy; generation of 3D retinal tissue with physiologically competent, light-sensitive photoreceptors; modeling brain tumors using genetically edited brain organoids; and brain organoids as a model to study Zika virus and SARS-CoV-2 infections. In the Neuromethods series style, chapters include the kind of detail and key advice from the specialists needed to get successful results in your laboratory. Comprehensive and cutting-edge, Brain Organoid Research is a valuable resource for researchers at various levels of learning, ranging from undergraduate students, early researchers, and advanced laboratories. This book aims to be instrumental in moving this developing field forward.
Mathematical Theory of Finite Elements
This book discusses the foundations of the mathematical theory of finite element methods. The focus is on two subjects: the concept of discrete stability, and the theory of conforming elements forming the exact sequence. Both coercive and noncoercive problems are discussed.. Following the historical path of development, the author covers the Ritz and Galerkin methods to Mikhlin’s theory, followed by the Lax–Milgram theorem and Cea’s lemma to the Babuska theorem and Brezzi’s theory. He finishes with an introduction to the discontinuous Petrov–Galerkin (DPG) method with optimal test functions. Based on the author’s personal lecture notes for a popular version of his graduate course...
Brain Organoids: Modeling in Neuroscience
This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.
Recent Developments in Discontinuous Galerkin Finite Element Methods for Partial Differential Equations
The field of discontinuous Galerkin finite element methods has attracted considerable recent attention from scholars in the applied sciences and engineering. This volume brings together scholars working in this area, each representing a particular theme or direction of current research. Derived from the 2012 Barrett Lectures at the University of Tennessee, the papers reflect the state of the field today and point toward possibilities for future inquiry. The longer survey lectures, delivered by Franco Brezzi and Chi-Wang Shu, respectively, focus on theoretical aspects of discontinuous Galerkin methods for elliptic and evolution problems. Other papers apply DG methods to cases involving radiative transport equations, error estimates, and time-discrete higher order ALE functions, among other areas. Combining focused case studies with longer sections of expository discussion, this book will be an indispensable reference for researchers and students working with discontinuous Galerkin finite element methods and its applications.
Scientific Computing in Electrical Engineering
This collection of selected papers presented at the 12th International Conference on Scientific Computing in Electrical Engineering, SCEE 2018, held in Taormina, Sicily, Italy, in September 2018, showcases the state of the art in SCEE. The aim of the SCEE 2018 conference was to bring together scientists from academia and industry, mathematicians, electrical engineers, computer scientists, and physicists, and to promote intensive discussions on industrially relevant mathematical problems, with an emphasis on the modeling and numerical simulation of electronic circuits and of electromagnetic fields. This extensive reference work is divided into five parts: Computational Electromagnetics, Device Modeling and Simulation, Circuit Simulation, Mathematical and Computational Methods, Model Order Reduction. Each part starts with a general introduction, followed by the respective contributions. The book will appeal to mathematicians and electrical engineers. Further, it introduces algorithm and program developers to recent advances in the other fields, while industry experts will be introduced to new programming tools and mathematical methods.
Computing with hp-ADAPTIVE FINITE ELEMENTS
With a focus on 1D and 2D problems, the first volume of Computing with hp-ADAPTIVE FINITE ELEMENTS prepared readers for the concepts and logic governing 3D code and implementation. Taking the next step in hp technology, Volume II Frontiers: Three-Dimensional Elliptic and Maxwell Problems with Applications presents the theoretical foundations of the
Programmable Planet
Honorable Mention, 2024 Richard Frisbie Award for Adult Nonfiction, Society of Midland Authors A new science is reengineering the fabric of life. Synthetic biology offers bold new ways of manufacturing medicines, clothing, foods, fragrances, and fuels, often using microbe fermentation, much like brewing beer. The technology can help confront climate change, break down industrial pollutants, and fight novel viruses. Today, researchers are manipulating life forms and automating evolution to create vegetarian “meat,” renewable construction materials, and cancer treatments. In the process, they are changing our concept of what life science can achieve. Is this a new industrial and informatio...
Spectral and High Order Methods for Partial Differential Equations ICOSAHOM 2014
The book contains a selection of high quality papers, chosen among the best presentations during the International Conference on Spectral and High-Order Methods (2014), and provides an overview of the depth and breadth of the activities within this important research area. The carefully reviewed selection of papers will provide the reader with a snapshot of the state-of-the-art and help initiate new research directions through the extensive biography.
Stress Challenges and Immunity in Space
This book explains how stress – either psychological or physical – can activate and/or paralyse human innate or adaptive immunity. Adequate immunity is crucial for maintaining health, both on Earth and in space. During space flight, human physiology is specifically challenged by complex environmental stressors, which are most pronounced during lunar or interplanetary missions. Adopting an interdisciplinary approach, the book identifies the impact of these stressors – the space exposome – on immunity as a result of (dys-)functions of specific cells, organs and organ networks. These conditions (e.g. gravitation changes, radiation, isolation/confinement) affect immunity, but at the same...
Large-Scale Scientific Computing
This book constitutes the thoroughly refereed post-conference proceedings of the 11th International Conference on Large-Scale Scientific Computations, LSSC 2017, held in Sozopol, Bulgaria, in June 2017. The 63 revised short papers together with 3 full papers presented were carefully reviewed and selected from 63 submissions. The conference presents results from the following topics: Hierarchical, adaptive, domain decomposition and local refinement methods; Robust preconditioning algorithms; Monte Carlo methods and algorithms; Numerical linear algebra; Control and optimization; Parallel algorithms and performance analysis; Large-scale computations of environmental, biomedical and engineering problems. The chapter 'Parallel Aggregation Based on Compatible Weighted Matching for AMG' is available open access under a CC BY 4.0 license.
