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This book explores the interplay of bubble dynamics and shock waves, covering shock wave emission by laser generated bubbles, pulsating bubbles near boundaries, interaction of shock waves with bubble clouds, applications in shock wave lithotripsy, and more.
This book highlights advances and prospects of a highly versatile and dynamic research field: Therapeutic ultrasound. Leading experts in the field describe a wide range of topics related to the development of therapeutic ultrasound (i.e., high intensity focused ultrasound, microbubble-assisted ultrasound drug delivery, low intensity pulsed ultrasound, ultrasound-sensitive nanocarriers), ranging from the biophysical concepts (i.e., tissue ablation, drug and gene delivery, neuromodulation) to therapeutic applications (i.e., chemotherapy, sonodynamic therapy, sonothrombolysis, immunotherapy, lithotripsy, vaccination). This book is an indispensable source of information for students, researchers and clinicians dealing with non-invasive image-guided ultrasound-based therapeutic interventions in the fields of oncology, neurology, cardiology and nephrology.
Electroporation is the forefront in tumor ablation. This book presents the basic principles and clinical applications of electroporation, including the latest research results and patient data. A comprehensive approach to the basic science behind the development of this ground-breaking technique and its introduction into clinical practice, the book discusses the entire spectrum of currently available reversible treatments, the emerging irreversible applications, and their impact on patient care. Clinical Aspects of Electroporation is the first book intended for clinicians on this extremely important and rapidly developing field.
The discovery and development of a biological active molecule with therapeutic properties is an ever increasing complex task, highly unpredictable at the early stages and marked, in the end, by high rates of failure. As a consequence, the overall process leading to the production of a successful drug is very costly. The improvement of the net outcome in drug discovery and development would require, amongst other important factors, a good understanding of the molecular events that characterize the disease or pathology in order to better identify likely targets of interest, to optimize the interaction of an active agent (small molecule or macromolecule of natural or synthetic origin) with thos...
A reflection of the intense study of the effects of electromagnetic fields on living tissues that has taken place during the last decades, Advanced Electroporation Techniques in Biology and Medicine summarizes most recent experimental findings and theories related to permeabilization of biomembranes by pulsed electric fields. Edited by experts and
Targeted therapies use specific therapeutic agents that specifically target a molecule that is involved in disease progression. By targeting these specific molecules, the molecular pathway of the disease development could be modulated thus inhibiting the disease progression. By specifically targeting a molecule involved in disease development, we can overcome potential side effects, increasing the precision of the treatment. Precision medicine approaches have been particularly successful in the field of oncology, where targeted therapies have been tested and developed for specific mutations or molecules that promote tumor growth. This Research Topic is centered around the use of therapeutic ...
Precision medicine is an approach that proposes customized medical care based on the individual characteristics of each patient. The rapidly emerging field not only holds great promise for diagnosis of disease and prediction of risk of developing diseases, but also offers the possibility of remarkably fine-tuned remedies to improve patient health while minimizing the risk of harmful side effects. Many technologies including genetics, informatics, and medical imaging, are rapidly expanding the scope of precision medicine. Among these technologies, imaging is poised to play a major role in the age of precision medicine. By characterizing anatomy, physiology and metabolism of the patient, medic...
This volume presents the proceedings of the 1st World Congress on Electroporation and Pulsed Electric Fields in Biology, Medicine and Food & Environmental Technologies (WC2015). The congress took place in Portorož, Slovenia, during the week of September 6th to 10th, 2015. The scientific part of the Congress covered different aspects of electroporation and related technologies and included the following main topics: · Application of pulsed electric fields technology in food: challenges and opportunities · Electrical impedance measurement for assessment of electroporation yield · Electrochemistry and electroporation · Electroporation meets electrostimulation · Electrotechnologies for foo...