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Sensing the Environment: Regulation of Local and Global Homeostasis by the Skin's Neuroendocrine System
The skin, the body’s largest organ, is strategically located at the interface with the external environment where it detects, integrates and responds to a diverse range of stressors, including solar radiation. It has already been established that the skin is an important peripheral neuroendocrine-immune organ that is closely networked with central regulatory systems. These capabilities contribute to the maintenance of peripheral homeostasis. Specifically, epidermal and dermal cells produce and respond to classical stress neurotransmitters, neuropeptides and hormones, production which is stimulated by ultraviolet radiation (UVR), biological factors (infectious and non-infectious) and other ...
The Neurobiology of Neurotensin
This cohesive precis of advances in our understanding of neurotensin describes its synthesis, release and degradation, molecular genetics, anatomy, studies on messenger RNA, receptors and mechanisms of action, together with interactions with the dopaminergic system.
Annals of the New York Academy of Sciences
Records of meetings 1808-1916 in v. 11-27.
