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This book brings together the biology and computational features of the basal ganglia and their related cortical areas along with select examples of how this knowledge can be integrated into neural network models. Recent years have seen a remarkable expansion of knowledge about the anatomical organization of the part of the brain known as the basal ganglia, the signal processing that occurs in these structures, and the many relations both to molecular mechanisms and to cognitive functions. This book brings together the biology and computational features of the basal ganglia and their related cortical areas along with select examples of how this knowledge can be integrated into neural network...
The anatomy and physiology of the basal ganglia and their relation to brain and behavior, disorders and therapies, and philosophy of mind and moral values. The main task of the basal ganglia—a group of subcortical nuclei, located at the base of the brain—is to optimize and execute our automatic behavior. In this book, Hagai Bergman analyzes the anatomy and physiology of the basal ganglia, discussing their relation to brain and behavior, to disorders and therapies, and even to moral values. Drawing on his forty years of studying the basal ganglia, Bergman presents new information on physiology and computational models, Parkinson’s disease and other ganglia-related disorders, and such th...
Discusses themes of current interest in the basal ganglia. The work provides tools with which to tackle the remaining questions and experimentation on basal ganglia systems.
Over the past 25 years the amount of data pertaining to the GABAergic function in the basal ganglia has increased dramatically. GABA and the Basal Ganglia - From Molecules to Systems is a comprehensive review of the current state-of-the-art of knowledge about the neuroanatomy, neuropharmacology and neurophysiology of the basal ganglia, focusing on its GABAergic microcircuitry. It serves as a complete reference to the body of knowledge about the basal ganglia, its constituent neurons, and their interconnections. This volume is designed to serve as a convenient all-in-one review and reference for experienced basal ganglia researchers as well as an introduction to the functional organization of the basal ganglia and its GABAergic circuitry for students and researchers new to the field.* Reviews the anatomy, physiology and pharmacology of the basal ganglia itself in addition to focusing on the GABAergic circuitry of the basal ganglia* Authors of each chapter leading internationally acclaimed experts in basal ganglia research
Computational neuroscience is the theoretical study of the brain to uncover the principles and mechanisms that guide the development, organization, information processing, and mental functions of the nervous system. Although not a new area, it is only recently that enough knowledge has been gathered to establish computational neuroscience as a scientific discipline in its own right. Given the complexity of the field, and its increasing importance in progressing our understanding of how the brain works, there has long been a need for an introductory text on what is often assumed to be an impenetrable topic. The new edition of Fundamentals of Computational Neuroscience build on the success and...
We live longer than ever before. Let this life-changing book show you how to make the most of your ‘wisdom years’. We are now experiencing one of the most significant — but not yet fully understood — revolutions in human life: the dramatic rise in life expectancy. This revolution does not imply, as most people usually think, that we’ve simply got more years of old age. Rather, it implies the formation of a new period in human life: the Age of Wisdom. This age is qualitatively different from the adulthood that precedes it and the old age that follows. People who are able to prepare themselves for this new age will be able to enjoy an active, wise and satisfying stage of life, which ...
There is a tradition of theoretical brain science which started in the forties (Wiener, McCulloch, Turing, Craik, Hebb). This was continued by a small number of people without interruption up to the present. It has definitely provided main guiding lines for brain science, the devel opment of which has been spectacular in the last decades. However, within the bulk of experimental neuroscience, the theoreticians some times had a difficult stand, since it was felt that the times were not ripe yet and the methods not yet available for a development of a true theoretical speciality in this field. Thus theory remained in the hands of a fairly small club which recruited its members from theoretical...
The Basal ganglia, to adopt a phrase of Churchill's, are "a riddle wrapped in a mystery, inside an enigma." And although there is a wealth of information available on them, this research field remains controversial due in part to the diverse number of disciplines involved. A Theory of the Basal Ganglia and Their Disorders provides a clear, coherent
Providing a step-by-step and practical account of how to model neurons and neural circuitry, this textbook is designed for advanced undergraduate and postgraduate students of computational neuroscience as well as for researchers in neuroscience and related sciences wishing to apply computational approaches to interpret data and make predictions.
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