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Glucocorticoid Signaling
This timely volume provides a comprehensive overview of glucocorticoids and their role in regulating many aspects of physiology and their use in the treatment of disease. The book is broken into four sections that begin by giving a general introduction to glucocorticoids and a brief history of the field. The second section will discuss the effects of glucocorticoids on metabolism, while the third section will cover the effects of glucocorticoids on key tissues. The final section will discuss general topics, such as animal models in glucocorticoid research and clinical implications of glucocorticoid research. Featuring chapters from leaders in the field, this volume will be of interest to both researchers and clinicians.
Molecular Pathogenesis of MODYs
Covering a broad and novel approach on the subject of MODYs, this book looks into the future of molecular genetic and biochemical research in this area. It is recommended reading for basic research scientists in the area of diabetes mellitus, academically oriented endocrinologists and clinical researchers.
Unraveling the Exposome
This volume presents a comprehensive overview of the science and application of the Exposome through seventeen chapters from leaders in the field. At just over ten years since the term was coined by Christopher Wild in 2005, this is the first, field-defining volume to offer a holistic picture of the important and growing field of Exposomics. The term “Exposome” describes the sum of all exposures (not only chemical) that an individual can receive over a lifetime from both exogenous sources (environmental contaminants, food, lifestyle, drugs, air, etc.) and endogenous sources (metabolism, oxidative stress, lipid peroxidation, chemicals synthesized by the microbiome, etc.). The first sectio...
The Role of Angiopoietin-like 4 in Lipid Homeostasis
Abstract The Role of Angiopoietin-like 4 in Lipid Homeostasis by Nora Elizabeth Forbes Gray Doctor of Philosophy in Molecular and Biochemical Nutrition University of California, Berkeley Professor Jen-Chywan Wang, Chair Alterations in the regulation of lipid homeostasis are major causes of metabolic diseases like obesity, insulin resistance and the metabolic syndrome. These diseases affect millions of people and therefore constitute a pressing public health concern. The mobilization of lipids is a key regulatory step in lipid homeostasis and the proteins that mobilize lipids from adipocytes to other tissues are therefore potential targets for therapeutic interventions. One such protein is an...
Directory of Graduate Research
Faculties, publications and doctoral theses in departments or divisions of chemistry, chemical engineering, biochemistry and pharmaceutical and/or medicinal chemistry at universities in the United States and Canada.
