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Comparative Genomics
Comparative genomics: an introduction: sequencing projects and model organisms (M. S. Clark). Drosophila melanogaster: a genetic tool (U. Schafer, H. Jackle). Tunicates: models for chordate evolution and development at low genomic complexity (W. R. Jeffrey). Fugu rubripes: a fish model genome (M. S. Clark, G. Elgar). The mouse and the genomic era (T. J. Wilson, F. Lazner, I. Kola, P. J. Hertzog). Quantitative Trait Loci in domestic animals - complex inheritance patterns (E. Lipkin, m. Soller). Comparative genomics of vertebrates and the evolution of sex chromosomes (J. A. M. Graves, S. Shetty). Insights into mammalian genome organization evolution by molecular cytogenetics (J. Wienberg, L. Froniecke, R. Stanyon). Index.
Monoclonal Antibodies in Transplantation
Experimental and clinical evidence presented in this book illustrates that antibodies expressing different specificities can be very effective in preventing or reversing established transplant rejection. Moreover, the data leads us to hope that the use of these new therapeutic agents may allow the induction of specific tolerance to transplant alloantigens which is the only means to avoid the major risks of sustained immunosuppression, namely an increased susceptibility to infection and tumor development. In this volume the editors combine contributions dealing with very practical aspects of the clinical use of monoclonal antibodies with a more general discussion on the developments one may foresee in the near future.
Atlas of Mammalian Chromosomes
A stunning visual collection of the banded metaphase chromosomekaryotypes from some 850 species of mammals, the Atlas of MammalianChromosomes represents an unabridged compendium of the state ofthis genomic art form. Bringing together information currentlyscattered throughout the cytogenetics literature for scores ofpublished and unpublished species, this atlas features high-qualitykaryotype images for nearly every mammal studied to date, making itthe most comprehensive assemblage of high-resolution chromosomephotographs available--a critically invaluable resource for today'scomparative genomics era. For every available species, the Atlas of Mammalian Chromosomespresents the best karyotype pr...
Pre-mRNA Processing
he past fifteen years have seen tremendous growth in our understanding of T the many post-transcriptional processing steps involved in producing func tional eukaryotic mRNA from primary gene transcripts (pre-mRNA). New processing reactions, such as splicing and RNA editing, have been discovered and detailed biochemical and genetic studies continue to yield important new insights into the reaction mechanisms and molecular interactions involved. It is now apparent that regulation of RNA processing plays a significant role in the control of gene expression and development. An increased understanding of RNA processing mechanisms has also proved to be of considerable clinical importance in the pa...
Marsupials
This 2006 book examines the exciting discoveries in the study of marsupials of the last 20 years. These discoveries have led to significant developments in our understanding of this unique group of mammals. The impact of these developments have been such that marsupials are coming to be seen as model organisms in studies of life history evolution, ageing and senescence, sex determination and the development and regeneration of the nervous system. This volume brings together information scattered throughout the primary literature. Coverage includes evolutionary history and management strategies as well as all aspects of basic biology. A complete listing of known species and a comprehensive list of references make this a unique repository of information on this fascinating group of animals.
Wildlife Review
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International Review of Cytology
International Review of Cytology presents current advances and comprehensive reviews in cell biology-both plant and animal. Articles address structure and control of gene expression, nucleocytoplasmic interactions, control of cell development and differentiation, and cell transformation and growth. Authored by some of the foremost scientists in the field, each volume provides up-to-date information and directions for future research.
Reproduction in Mammals
"Newborn mammals can weigh as little as a dime or as much as a motorcycle. Some receive milk for only a few days, whereas others nurse for years. Humans typically have only one baby at a time following nine months of pregnancy, but other mammals have 20 or more young after only a few weeks in utero. What causes this incredible reproductive diversity? Reproduction in Mammals is a fascinating examination of the diverse reproductive strategies of a broad spectrum of mammals and the ways in which natural selection has influenced that diversity. While accounts of reproduction in individual taxa abound, this unique book's comprehensive coverage gathers stories from many taxa into a single, cohesiv...
c-Myc Function in Neoplasia
1. 1 SCOPE OF BOOK n explosion of novel findings in the past decade has contrib A uted to the great progress toward understanding the biology of human cancers. Much of this progress can be attributed to our abil ity to dissect many biological processes at the molecular level. Most spectacular is the technology of molecular biology that allows identi fication and characterization of genes that participate in the genesis of human cancers. Three major groups of genes appear to play out the drama of cancer development: tumor suppressor genes, mis match repair genes, and oncogenes. The tumor suppressor genes 1 encode products that are inhibitory to cell proliferation. The loss of these inhibitors...
Chromosomes Today
Chromosomes Today volume 14 records the plenary proceedings of the 14th International Chromosome Conference, presenting an overview of the current concerns in plant, animal and human cytogenetics. This volume provides up-to-date information regarding relevant aspects on structure, function and evolution of chromosomes, meiosis, sex chromosomes, and cancer cytogenetics. It contains invited contributions from some of the world's leading experts in the field.
