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Annotation The field of toxicology has developed a well-characterized set of techniques to assess the behavioral and histopathological consequences of exposure to environmental insults using a number of animal models. These techniques are suitable for determining crude endpoints of exposure such as death, but are not optimal for assessing the more subtle effects of very low level or multi-agent chemical exposures, nor do they offer mechanistic explanations at the molecular level. This book is designed to have a mix of chapters devoted to classical toxicology followed by those focused more on the emerging techniques of toxicogenomics and proteomics. In this way, the relevance of new technologies such as gene arrays to classical toxicologic problems is made evident. Finally, because the worst of the world's toxicology problems reside in developing nations while the latest technical developments are occurring in the industrial nations, we sought to provide a balance of both scientific and geographical perspectives from researchers engaged in toxicology and public health research.
The first edition of this book, Chemical Warfare Agents: Toxicity at Low Levels, was published just prior to the terrorist attacks of September 11th, 2001. Reflecting a greater sense of urgency within the field of chemical defense since this event, research related to chemical warfare agents (CWAs) continues to expand at a remarkable pace.
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Bringing together the recent and relevant contributions of over 125 scientists from industry, government, and academia in North America and Western Europe, Alternative Toxicological Methods explores the development and validation of replacement, reduction, and refinement alternatives (the 3Rs) to animal testing. Internationally recognized scientist
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The first accessible reference to cover the history, context, current issues, and key concepts surrounding biological, chemical, and nuclear weapons. A collection of information on everything from aerosols to zones of peace, these two volumes cover historical background, technology, and strategic implications of biological, chemical, and nuclear weapons, thus providing facts, terms, and context needed to participate in contemporary policy debate. This encyclopedia is the only comprehensive reference dedicated to the three types of weapons of mass destruction. With over 500 entries arranged alphabetically, volume one covers biological and chemical weapons, while volume two focuses on nuclear ...
Faculties, publications and doctoral theses in departments or divisions of chemistry, chemical engineering, biochemistry and pharmaceutical and/or medicinal chemistry at universities in the United States and Canada.