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This textbook provides a concise introduction to optimal experimental design and efficiently prepares the reader for research in the area. It presents the common concepts and techniques for linear and nonlinear models as well as Bayesian optimal designs. The last two chapters are devoted to particular themes of interest, including recent developments and hot topics in optimal experimental design, and real-world applications. Numerous examples and exercises are included, some of them with solutions or hints, as well as references to the existing software for computing designs. The book is primarily intended for graduate students and young researchers in statistics and applied mathematics who are new to the field of optimal experimental design. Given the applications and the way concepts and results are introduced, parts of the text will also appeal to engineers and other applied researchers.
This volume contains the majority of the papers presented at the 5th Inter national Workshop on Model-Oriented Data Analysis held in June 1998. This series started in March 1987 with a meeting on the Wartburg, Eisenach (Germany). The next three meetings were in 1990 (St Kyrik monastery, Bulgaria), 1992 (Petrodvorets, StPetersburg, Russia) and 1995 (Spetses, Greece). The main purpose of these workshops was to bring together lead ing scientists from 'Eastern' and 'Western' Europe for the exchange of ideas in theoretical and applied statistics, with special emphasis on experimen tal design. Now that the separation between East and West has become less rigid, this dialogue has, in principle, bec...
This open access book contains review papers authored by thirteen plenary invited speakers to the 9th International Congress on Industrial and Applied Mathematics (Valencia, July 15-19, 2019). Written by top-level scientists recognized worldwide, the scientific contributions cover a wide range of cutting-edge topics of industrial and applied mathematics: mathematical modeling, industrial and environmental mathematics, mathematical biology and medicine, reduced-order modeling and cryptography. The book also includes an introductory chapter summarizing the main features of the congress. This is the first volume of a thematic series dedicated to research results presented at ICIAM 2019-Valencia Congress.
This book presents novel statistics methods and reproducible software that helps to solve challenging problems in biomedicine. Specifically, it consists of a collection of 11 chapters contributed by some of the leading experts in the mathematical and statistical field which address new challenges in very disparate biomedical areas, such as genomics, cancer, circadian biology, microbiome, mental disorders, and more. The mathematical rigor is written in a user-friendly way to serve a general biomedical audience ranging from trainees or students to doctors, as well as scientific researchers, university departments, and PhD students.
This volume contains the proceedings of the 8th Workshop on Model-Oriented Design and Analysis. It offers leading and pioneering work on optimal experimental designs, both from a mathematical/statistical point of view and with regard to real applications. Scientists from all over the world have contributed to this volume. Primary topics are designs for nonlinear models and applications to experimental medicine.
Since the beginning of the World Health Organization, many of its staff members, regional offices, member states, and directors-general have grappled with the question of what a 'spiritual dimension' of health looks like, and how it might enrich the health policies advocated by their organisations. Contrary to the wide-spread perception that 'spirituality' is primarily related to palliative care and has emerged relatively recently within the organisation, this study shows that its history is considerably longer and more complex, and has been closely connected to the WHO's ethical aspirations, its quest for more holistic and equitable healthcare, and its struggle with the colonial legacy of i...
This book arises from the International Spring School "Advances and Challenges in Space-Time modelling of Natural Events," which took place March 2010. It details recent developments, new methods and applications in spatial statistics and related areas. This book arises from the International Spring School "Advances and Challenges in Space-Time modelling of Natural Events," which took place March 2010. It details recent developments, new methods and applications in spatial statistics and related areas.
This volume is the proceedings of the 4th International Workshop on Model-Oriented Data Analysis. This series of events originated in 1987 at a meeting in Eisenach, that successfully brought together scientists from numerous countries of the 'East ' and 'West'. Now that this distinction is obsolete dialogue has been greatly facilitated, providing opportunities for this dialogue, however, is as vital as ever. The present meeting at Spetses, Greece from 5th to 9th of June 1995 again assembles statisticians from all over the world as this book documents. The hospitality offered by the University of Economics of Athens and the Korgialenios School made it possible to organize this workshop. The e...
This volume contains pioneering contributions to both the theory and practice of optimal experimental design. Topics include the optimality of designs in linear and nonlinear models, as well as designs for correlated observations and for sequential experimentation. There is an emphasis on applications to medicine, in particular, to the design of clinical trials. Scientists from Europe, the US, Asia, Australia and Africa contributed to this volume of papers from the 11th Workshop on Model Oriented Design and Analysis.
This book involves ideas/results from the topics of mathematical, information, and data sciences, in connection with the main research interests of Professor Pardo that can be summarized as Information Theory with Applications to Statistical Inference. This book is a tribute to Professor Leandro Pardo, who has chaired the Department of Statistics and OR of the Complutense University in Madrid, and he has been also President of the Spanish Society of Statistics and Operations Research. In this way, the contributions have been structured into three parts, which often overlap to a greater or lesser extent, namely Trends in Mathematical Sciences (Part I) Trends in Information Sciences (Part II) ...